Hi @beatit2027 sorry for your diagnosis and that chemo is on the menu for you.
Your questions are good ones, but probably only questions your oncologist can answer, as your diagnosis is unique to you. My journey also involved chemo which I’m just over half-way through. I started in November and will finish in March. I have a PICC line, and am glad of it to be honest. It was a bit bothersome to start with, but I am used to it now.
I think some people do have chemo with cannula with mixed reactions.
Definitely have a chat with your oncologist about it and they can guide you. Sorry not to be more informative than that. Good luck and if you feel like it, do keep us posted on how you’re getting on.