I had a PICC line, without any choice, but because I already have a long-term autoimmune disease which involves needles, all my veins are hard and scarred, so this was the only option for chemotherapy.
I was lucky in the 6 months, I didn’t need it flushed, but was meticulous at keeping it clean and dry, so I could avoid it potentially having to be removed.
It was good for chemotherapy without any hassle and I managed during the summer to keep it covered with 3quarter length tops. The only downside, was as my other condition requires blood tests, the phlebotomy department at the hospital wasn’t trained to use PICC lines for blood tests, so it was painful getting blood (the PICC line has to go on the opposite side of a mastectomy, which just happened to be my better arm)
All in all, I was glad when it was out. That was almost 3 years ago and I still have hole in my arm and skin irritation from being allergic to one of the dressings.