Hi all I have not signed on a while but basically things have not been good. My tumour in the Liver started growing again back in April Capcebine stopped working. Tried hormones for 3 months but now the tumour is 5.5cms. Started Navelbine last week. Felt well until Sunday severe pain in mouth jaw area, could not eat or drink. This started to fade late Monday but was replaced with severe headache on my right side. Tried every painkiller nothing helped. I have been vomiting all day today. I was due back at hospital today for more chemo. To cut a long story short had CT scan of brain and thank god it was clear. (stressful!!!) No chemo was given today and Constultant is deciding were we go from here. Reduce chemo or change. Please has anyone else had this problem with this chemo?
Hi Cheezy, I have been on navelbine for over a yr with very few problems. I do have some nerve damage which causes severe muscle cramps, but never a problem like yours. I hope you have better luck next dose. Funnyface
I had slight problems with vinolrebine, noticeably neuropathic, and that included an aching jaw after cycles two and three. It stopped happening after that. You may be abnormally sensitive to this aspect of the drug. I hope your consultant can sort things out.
Hiya Cheezy,
Im sorry I can’t help you regarding Navelbine but I had similar problems and worse with Capecitabine.
I had severe pain in my jaw, headaches, horrendous heartburn which Lanzoprozole, omeprezole & ranitidine did not touch,
blurred vision & severe dizziness and all that started the day after I started taking the tablets! I only managed 3 days then had to stop for a few days and re-start them once I felt better. Well, I re-started them at half the dosage prescribed for me and I still had the side effects.
Consultant said I must have been sensitive to a component in the drug so we had no choice but to take me off them.
I am now on Taxol & Gemcitabine…which im tolerating quite well.
I had problems last year with my 1st Taxotere (ended up in hospital for a week), had the dosage reduced by 25% and that did the trick.
If you reduced the dosage the effects you “may” still get won’t be as harsh as they are now, but do you think you could cope with them if you still got them?
I know that a lot of ladies on here have managed quite well on dose reductions, I tried it with one chemo which worked, tried on another, it didn’t work but we wouldn’t have known that if we hadn’t tried.
Is Navelbine an I.V chemo or tablet form? Only problem you have is if it I.V form you will have put up with it until it is out of your system, tablet form can be stopped straight away and after a day or so the effects have worn off.
I hope you feel better soon and get your treatment sorted out.
Please keep us updated.
Julie
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Thanks for the advice girls. I finally got some respite from the pain in that I attended my Chriopractor. I had not seen him in over a year. He examined me and said that there was nothing wrong with my head it was my neck and shoulders that were the problem. He said my body especially my right hand side was in shock from chemo, liver, bony mets and getting the picc line fitted. I have had two treatments with him and I am beginning to feel a bit better. I hope the week from hell is finally over. I have decided to give the chemo another try with a reduced dose on thursday. As i think the Chriopractor can help me with the pain and hopefully it will not be as bad. If not then a change of Chemo to Gemcitabine. My liver tumour is 5.5 cms and they said I would do 9 cycles of vinorbline and then scan and if I had some skrinkage they would consider ablation. This is what I am aiming for. Has anyone every had this and does it work well. Many thanks for your comments it really helps to be able to talk to people who understand.
Thanks Cheezy