Hi there,
I am also taking Prozac and have been for about 3 years. I am supposed to be starting Tamoxifen after chemo and have been told I must come off the prozac which has been a lifesaver for me and have been very upset about this.
I have been in contact with my onc who was bemused that I needed to know asap if I had to come off the prozac as it will have to be very slowly, like over months as I have been on it so long and what meds he suggest as alternative. He decided as am perimenopausal to check hormone levels. If postmenopausal will only need to go on aromatase inhibiter instead of both! Blood test showed perimenopausal or menopausal so will have to wait till MDT meeting tomorrow to see what is decided. This is another of those things bc takes over and is really frustrating as a result!
Anyway I feel if antidepressants are needed they are helpful and sometimes we need help and if one doesnt agree with you tell the doctor and try something else, they are definately not one fits all solution and they do take about 3 weeks to help you feel more yourself and you can feel worse at first but if you can persevere it can really be worthwhile, hope this helps and excuse my venting before!
Hugs and hope you feel better soon, Bev x
Vent away! 
If it’s any help, I was on an antidepressant (Velnaflaxin)and tamoxifen at the same time. My opinion is you need them if your having side effects off the Tamoxifen.
Jen xxx