That’s interesting that you think taking it at night might be better for fatigue. I’ve been grimly sticking to the same routine of taking it in the morning with a mug of green tea not daring to change but I might give the evening a go to see if it makes any difference. I’ve got to the stage where I’ll try anything. I’ve been on Accord for two years so have no experience of other brands.
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I’ve consistently taken it at night so can’t comment on that part but after a few not too awful months on Accord I was given a different brand & within a week I had the most awful insomnia, hot sweats returned with a vengeance, I was exhausted & felt truly awful. Thankfully my pharmacy was able to place another Accord order & I’ve done my best to explain to them that this needs to be my standard going forward-not convinced they’ll always be able to do it but that 10 days was enough for me to say I can’t take this a second longer. So for me it seems yes the brand does make a difference & I can’t explain that!
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I put off starting Letrozole until after my holiday as I had read a lot of scare stories and wanted just to enjoy feeling normal again after dreadful chemo and easy surgery. Started on Sept 4th. So far, so good I think. Get odd flashes of clamminess - mostly afternoons and evenings. At night sometimes have to kick off my covers but not really unusual. Only lasts a few minutes. Right knee sometimes feels stiff and heavy but nothing like it was on chemo. Feel a bit sleeper in the evenings than normal but have also started radiotherapy this week. (I had my wide excision surgeryin April after 6 rounds of chemo. )Haven’t put on weight but struggling to lose the weight I gained on holiday. I take my pill around midnight. ( Mostly go to bed around 1 am) Hopefully the side effects won’t get any worse as I was really dreading taking the Letrozole after reading other people’s reactions. Similarly, so far, no side effects from the radiotherapy which I was also dreading. Fingers crossed normal life can continue. Just to add, I had mild side effects from first zoledronic acid infusion also on 4 Sept. (Very sleepy the next day and a few bouts of shivering). 3 more doses of trastuzumab to go . So if anyone out there is facing these treatments and worrying as I was, just give them a try. They may not be as bad as you feared. Hope I am not speaking too soon but as I said so far so good