hi can any one offer me some advise i had triple negative breast cancer and i received my results from genetic team which were varient unknown so as it wasnt conclusive either way ive opted to have overies removed had app to day and gynogolegist said there would be no point as it not benefital as my cancer was not hormone based has any one else come across this reguarding preventative surgery having triple negative im in a high risk of a reacurrance thanks xxx
Not sure if it was your post or one very similar I replied to.
But basically you need to look at your personal and family history. Eg what age were you at diagnosis, who else had bc and what age were they, Is there any ovarian cancer. Is anybody else innthe family affected by breast, ovarian, prostate or pancreatic ca willing to be tested for the same VUS? This is often a good start to find out if it actually is significant in your family.
The gynaecologist seems to be looking in reference toy you bc treatment with regards to the oophorectomy rather than your family history.
You don’t need a confirmed gene mutation to have an ooph if you have a family history of breast and ovarian or just ovarian many will consider the op based on that. You can also ask for a second opinion if not happy with answers. Not sure if the marsden is accessible to you but they are very up their genetics.
We treat VUS the same as somebody who has no mutation found. Basically your risk is the same today as it was at diagnosis not increased and not decreased so if you are already high risk as opposed to moderate risk you may still find it useful to discuss bilat mx… Having the chat doesn’t commit you to surgery.
Maybe need to speak to genetic team some more… Write a list if questions.
With regards the surgery if you went down the route of all this very radical surgery and later found that the VUS was not significant and you were just unlucky to get cancer how would you feel about it?
Take care
Lulu xxxx
hi lulu34 im new to this site so was prob a similar post thanks for your reply i was 38 when diagnosed a yr younger than my aunt when she had bc and she was clear for two yrs before it returned to her overies and unfortunatly spreed to whole body my nan had bc had a mas and is still doing well her sister also had bc so my dad has been tested due to his sister and my nan (mothers side) has also been tested i think i just worrying about getting overian cancer and it not being detected in time i dont feel the need for a dm and after reading what you said about vus i feel i dont need to go down that route i think i need to get things in perspective thanks again wishing you well xx