Endo predict borderline

Hi I was diagnosed with G2 invasive cancer in December 2021 …had loads of delays and finally had mastectomy on 9/3 /22    my first Oncologist appt  was last week and final  histoly report addendum now says cancer is grade 1 .which is good but all previous biopsies said grade 2! I was expecting to be told I needed radio and hormone drugs but now as endopredit score is 11 and I have 3mm cancer in one sentinel node  decision is with me. I am scared that all the side effects of Chemo  for a 3% overall reduction in risk. Struggling with decision but know further delays will not help …anyone been in a similar position?   

Hi Maggi74,

Like yourself, I’m of the mind that the possible 3% benefit of the chemo just doesn’t sound enough for me - I’m really struggling to get my head around possibly making myself really ill to make myself better ?‍ :female_sign: And there are no guarantees either way with this crappy disease :frowning_face:
I am due to get my results of the oncotype dx test tomorrow so could be in exactly the same position as you tomorrow Such massive, life changing decisions for us all to make.

Sendings hugs for now, take care x

Hi @Maggi74  

I haven’t met the oncologist yet - my first appointment is next week. I perhaps have a clearer case for chemo than you, as I have triple negative BC, so there aren’t other treatments for it, and it’s grade 3. My independent research suggests chemo would reduce my risk of dying of BC within 5 years by around 40%, but in absolute risk terms, it’s from 16% to 6%. What helped me was to look at my life expectancy and the quality of life in each scenario. Sadly, I have a maths / stats background and tend to reduce everything to a spreadsheet.  At my age (65), it all seems finely balanced, as I also don’t want to impact the remaining time with being ill through chemo I have if I am one of the unlucky ones who is going to die anyway. It leaves me rather conflicted. If I was materially younger, I would put myself through the chemo. If I was materially older, I would definitely not have chemo. I am hoping the oncologist can shed more nuance on this.