I have been having a break from letrozole and the breast cancer nurse is calling me this week to discuss the next step. I have read that some people find Exemestane easier to take - I have a history of urine infections , particularly bad when first started letrozole 3 years ago but not too bad now. I have read that Exemestane can cause urine problems ?
Has anyone who has had problems with UTI’s managed ok on Exemestane or has it made them worse?
I was on Examastane for 7yrs. My understanding is its the low estrogen level that contributes to bladder infections. So yes I did start having repeat bladder infections. I then found research on high strength cranberry tablets creates a hostile environment so bacteria cant thrive in the bladder. Doesnt work for everyone but works for me……and doing this Ive managed to avoid low dosing of antibiotics that my GP advised for several years now. If I stop taking the tsblets the problem reoccurs. Ive not been on examastane for two years but the problem remains as me estrogen remains very low. Im post menopausal.
Hi
I am on letrozole and did have a UTI a couple of months ago. About 6 years ago I had a chronic UTI, whereby the short courses of antibiotics just did not clear it up. I sought advice from a specialist in this field, Dr Cat Anderson, and I was under treatment from her for about 9 months. One of the treatments she recommended is to take D-Mannose tablets. I admit I stopped taking them. Since I had a UTI recently I have started to take them again, and fingers crossed 
no further problems. You can get them online.
My onco prescribed Ovestin cream which has been a big help. It helps prevent UTI’s.
Im on Exemestane - i stay well hydrated and keep an eye on personal hygiene.
I also kerp a record of all side effects and have a four to six week break every 12 or so weeks.
Hi, I got them a lot before going on HRT (aged 55) and when I had to come off it due to the BC this time last year (aged 58)they came back horrifically again before I even started hormone therapy. Because of my history and how I could barely walk the oncologist I saw in March agreed to my continuing with Ovestin (I didn’t really use it when I was on systemic as I didn’t need it although it was on my prescription). I started on Letrozole in March which I found unbearable due to joint pain so was swapped to exemastane in July which I tolerate better. I also take Methenamine hippurate (via GP prescription) twice a day. I take optibac for women in the middle of the day, (well away from the methenamine) I use d mannose (nature supplies)and “ ultimate UT” powders (from pelvic relief) both prophylactically, when my bits feel ‘off’ and after sex. A private GP recommended rinsing after urinating/bowel movements (I sit on the bath side and spritz with the shower head) and applying dermol 500. I now only apply it when I feel dry or sore or if I’m about to do a long walk. I use the yes moisturizer and lube as well. I spend a fortune and I’m lucky to be able to afford it but I’ve been just about ok since being on this combo and am able to have sex once a week. I weep for the before meno/BC me who would have been horrified at only once a week but I now take what I can get and try to be grateful 
People really underestimate the absolute life destroying misery of recurring and chronic UTI. There’s a really proactive research/support charity which I recommend signing up to. It’s called Live UTI free and it’s run by women. Check out their YouTube videos too. I wish you luck. 
I’m on exemestane - I had lots of UTIs during and after chemo so not sure if it was always the exemestane that was causing them - but the GP prescribed me with estrogen pessaries - game changer. GP didn’t blink - just said it’s safe, go for it. Oncologist agreed. I haven’t had one since. I get the occasional discomfort day but no utis.
Im on Exemestane. Ovestin a game changer. Way more comfortable and no utis.