This is an overview from the American Cancer Society:
That’s a good, fair summary - thanks.
bump
Hello finty,
I was wondering if you or anyone else had spoken to their oncologists about IP6 yet?
Wandyx
No I’m not due to see her for a month or so. Does anyone else have an appointment sooner? It’s been used in lots of human trials for other illnesses, so will check those out for side effects too, but if it’s as benign as claimed I think I might just go ahead anyway.
Coming from a position of complete ignorance here! Which foods contain IP6 and can it be bought as a supplement?
Lilac
I’ve read loads on the Internet I’ve asked my gp he told me to go for it yes u can buy it in supplements the se are v small no onc will say take it because it’s not been tested it also says it enhances chemo also I have spoke to a company who sd if worried don’t take it when having chemo hope this helps tc laura
Lilac,
It can be found naturally in brown rice, beans, wheat bran corn sesame seed and other hi fibre foods. It is available as a supplement but I’m not sure of dosages.
It seems it may aid tamoxifen in its work as well as being efficacious in surpressing tumour growth and spread in its own.
Elinda posted some links a bit earlier I believe which gives more info.
Wandyx
The guy that has done most of the ground work on IP6 is Prof AbulKalam M. Shamsuddin of the University of Maryland Medical School. He recommends taking it at least an hour before meals. I’ve just read some research on lung cancer patients to test dosage of IP6.
Laura it’s great your GP said to go for it - had he/she heard of it before?
finty
Hi finty
He knew a little about it but prob not as much as us now lol he sd they are regimented to only use approved drugs even if others work he sd he knew patients who got great results just by changing their diet I look at it as what have I got to loose its no where near as chemo and I can stop at anytime my onc sd he will look at it if I get it but cldnt comment because it had not been tested
Hello Finty and everyone.I have been doing a fair bit of research in to IP6 and there are hundreds of websites ! please don’t shoot the messenger for any comments i make.Most of the remarks/testimonials i have read have been positive although there were a couple of negative ones.IP6 is apparently beneficial in a number of ailments.I searched,first of all,for side-effects,as if these were bad,i wouldn’t want my wife to use it! The only ones i can find are problem with blood clotting,possible anemia and weaked bones from poor calcium uptake.However,i have been unable to actually find a testimonial where someone has suffered from any of these effects.Apparently IP6 is already present in every cell in the body,and can be ingested via whole grain foods like bread & rice.My wife’s GP told me,(off the record)that he has heard of people controlling cancer just through diet.There was a website which i will try to find which went into explicit detail about exactly what IP6 does in the body and it’s mind-boggling.I shall try and get a link on here but unfortunately i am no technophile !
This is the link for the website.http://www.naturalnews.com/Images/NaturalNews-Logo_360x100.gif
Thanks Husband.
On a different subject, I highly recommend anyone with a sweet tooth read this article. It’s good but quite long - the stuff about sugar, insulin, growth factors and cancers starts on page 8. It seems there is some very interesting research going on at the moment at the top US cancer hospitals to try and develop drugs that stop insulin triggering cancer development. Good to hear - but in the meantime we can achieve the same results by cutting down on sugar and other dietary sources of insulin growth factors.
nytimes.com/2011/04/17/magazine/mag-17Sugar-t.html?pagewanted=1&_r=1&emc=eta1
finty
As you know, I’m not totally convinced by many of the dietary theories, but I do believe that regular consumption of refined sugar, and red meat could be implicated.
I think in most cases the body deals with extremes in diet, but refined sugar effects insulin levels and leads to the the laying down of toxic fat (which in turn produce oestrogen), and red meat literally rots it way through the digestive system (and that cannot be healthy).
Someone did an interesting post about metformin, and the belief is that it lowers oestrogen production by regulating insulin levels, and redistributing fat.
This research on sugar is very interesting - and a thought occurs to me - so much evidence says that cancer is not stress related but I’m convinced that cortisol from the adrenal gland can cause metabolic imbalance that can be linked to cancer - so another thought has occurred to me - COMFORT EATING and stress and sugar - and link with triggering cancer? and oh dear I’m looking at my OH’s Metformin after reading the links about research on its use in cancer treatments - does anyone know where the trials are being carried out? Anyway will now snack on oatcake and houmous and think positive thoughts about IB6 too!
Frances here’s a link to all the metformin and breast cancer research:
Many thanks Flinty - I’ve found stage 3 trials in USA, Canada and Milan - but none in UK. Do you know of any over here?
I haven’t heard of any here - but the oncology community here seems to be following it closely. My oncologist told me she thought diabetic drugs were going to be the “next big thing” for breast cancer, and was adamant that cutting down on sugar was highly advisable - she’s at a major cancer centre in London. It’s all very new though - metabolic syndrome itself was only recognised about 8 years ago I think, so all the research coming together linking high sugar diets, insulin resistance, obesity, IGF’s and cancer is all very recent - I’m sure we’ll hear much about it in years to come.
From the article I linked to, it’s apparently the pet project of the Head of Sloan Kettering - one of the top cancer hospitals in the world - which by itself should be enough to take it seriously.
This excerpt from the NY Times article gives an example of the calibre of people working on this issue, at very serious research centres, which is very encouraging:
"As it was explained to me by Craig Thompson, who has done much of this research and is now president of Memorial Sloan-Kettering Cancer Center in New York, the cells of many human cancers come to depend on insulin to provide the fuel (blood sugar) and materials they need to grow and multiply. Insulin and insulin-like growth factor (and related growth factors) also provide the signal, in effect, to do it. The more insulin, the better they do. Some cancers develop mutations that serve the purpose of increasing the influence of insulin on the cell; others take advantage of the elevated insulin levels that are common to metabolic syndrome, obesity and type 2 diabetes. Some do both. Thompson believes that many pre-cancerous cells would never acquire the mutations that turn them into malignant tumors if they weren’t being driven by insulin to take up more and more blood sugar and metabolize it.
What these researchers call elevated insulin (or insulin-like growth factor) signaling appears to be a necessary step in many human cancers, particularly cancers like breast and colon cancer. Lewis Cantley, director of the Cancer Center at Beth Israel Deaconess Medical Center at Harvard Medical School, says that up to 80 percent of all human cancers are driven by either mutations or environmental factors that work to enhance or mimic the effect of insulin on the incipient tumor cells. Cantley is now the leader of one of five scientific “dream teams,” financed by a national coalition called Stand Up to Cancer, to study, in the case of Cantley’s team, precisely this link between a specific insulin-signaling gene (known technically as PI3K) and tumor development in breast and other cancers common to women."
finty
Thanks for that info Finty, I’m so interested in this research especially as a sweet-toothed person.
You’re right Frances, simply put the body’s stress response is inextricably linked to glucose and insulin production. The purpose of the stress response is to prepare your body for ‘flight or fight’, and integral to that is the formation of new glucose, and the mobilisation of this and stored glucose into the blood stream for energy. Hence insulin is produced to metabolise the glucose.
Cortisol is a steroid hormone, and as you probably know prolonged steroid use causes diabetes - for the reasons stated above. Stress/comfort eating just provides more stores of glucose for use (and often more stress, owing the the guilt factor), and can lead to insulin resistance so that the body’s cells are unable to metabolise the glucose properly. I wonder how insulin resistance affects cancer cells - can they still metabolise the glucose effectively? Just a thought!
xx