Frequency for zoldex injections


I am wondering if anyone knows what the correct frequency for these zoldex injections, is it every month or every 3 months , so confused no one seems to be clear , the rationale to have it every month or after 3 months I have failed to get a concrete explanation from breast nurses or GP

Hi lcat

I had zoladex injections once a month which seems to make sense to me. I’ve not had them for a few years though, so I don’t know if things have changed. At the time my consultant said that they are more effective if you have them monthly.

Sue xx

Hi, I started Zodalex Injections monthly June 2022 but once Id finished chemo and signed the consent form for radiotherapy in December 2022 he changed it to once every 3 montht with my GP which personally is easier for me.

Its basically a higher dose to last for longer therefore not needing to go to your GP or cancer ward as often if your not in active treatment Im guessing. As once my chemo was over the chemo nurses were very set on me needing to get these done through my GP.

It might be worth speaking to your oncologist/ cancer unit about the hormone treatment.

Hope this helps and that your doing as well as can be.

All the best.

Hi @lcat

I have just had my third zoladex injection.

This leaflet tells you all about it (they refer to it as Goserelin as Zoladex is the brand name but same thing!). I’ve cut and paste the text from it which should answer your question:

For primary breast cancer, it is recommended that goserelin is given every 28 days (four weeks). The injection is called a ‘depot injection’, which means that the drug is steadily released into the bloodstream over the four weeks. Goserelin is also available as a three‑monthly injection for the treatment of other types of cancer. However, having goserelin in this way is not usually recommended for treating breast cancer as there is not enough evidence that it suppresses oestrogen levels enough. This is particularly important if you are having goserelin alongside an aromatase inhibitor. Goserelin may be given less frequently for secondary breast cancer. Your specialist can talk to you about this in more detail.

Hope that helps x

Hi there hope you are well. I was having zoledex monthly for a year, but recently i had an oophorectomy. I believe you can have them every 3 months, best to chat with your oncologist. I decided on the oophorectomy as i am stage 4 and i was starting to hurt from the implants.
Sending hugs sister 🩷🩷

I had a zoldex injection monthly for 5 years.
My treatment was 23 years ago.
Things are changing all the time they’re learning more .

Hi I’ve been on Zoladex for 2 years… hoping my next injection is my last! I have had them every 28 days. The pharmacy at the surgery confirmed this timescale. My nurse is brilliant we book a couple of appointments ahead as she’s so busy. Hope all goes well for you.


Hello Icat

Thank you for your post.

Zoladex is usually recommended to be given every 28 days, although it is also available as a 3 monthly injection which can be considered in some cases, as @Sue_C and @KirstieF mention.

We would suggest you speak with your treatment team again for them to clarify how often they advise for you to have the zoladex. Although you say your breast care nurse has not been able to help, you may want to ask to speak to your oncologist to answer your questions.

Do call our helpline if you would like to talk this through or have any further questions. The helpline team have time to listen to your concerns, talk things through and signpost you to more support and information. Your call will be confidential, and the number is free from UK landlines and all mobile networks. The number is 0808 800 6000, (Relay UK -prefix 18001).

If you would prefer one of our nurses to call you. To do this, please complete this form ticking the box agreeing to a call back.

Our usual opening hours are Monday to Friday 9am - 4pm and 9am -1pm on Saturday.

We are closed on Monday the 28th August for the bank holiday.

Out of hours you can leave a message and we will call you back when we next open.

Best wishes


Breast Care Nurse

Please read the Ask Our Nurses disclaimer Full details on how we collect and use your data can be found in our Privacy Policy

This thread will now be closed from further replies. If you have any additional questions or would like to provide feedback, please start a new thread.