Hi ive had my 4th herceptin today (2nd via injection) in thigh. The nurse for some reason gave it over nearly 15 mins instead of the usual 5 mins. Soon as needle out I looked down to quite a big lump. when i checked again after a short while this big lump was now at least the size of a cricket ball! I the nurse to have a look and they got a young doctor in who said it could be a local reaction and have given me some Piriton. this evening the lump it still the same and i’m just wondering as i’m also feeling perfectly fine if the Herceptin is just that under my skin?? Its a big round circle around the injection site. I just wondered if anybody else have experienced this please?