In my understanding, you can have tamoxifen after oophorectomy. Also, try exemestane. I couldn’t handle letrozole but I am doing much better on exemestane.
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Hi Holly - I was on Letrozole for about 8 mos when the really uncomfortable side effects kicked in, random diarrhea, total body insane itching, muscle pain so bad that I could hardly get up from a seated/lying position or walk when once vertical. Finally decided that at my age (almost 83) I didn’t want the next ten years to be like this. I talked with oncology PA and she agreed. I quit Letrozole about 2 weeks ago. Feeling a little better, but I am relieved to learn from others that the side effects can go on for months even after stopping. I don’t think I will try another aromatase since they all sound the same. God bless those who tolerate it. All the best to you and others. Foxglove
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