Thank you @bordercat, that’s really useful.
@lola25 I had chemotherapy. One tumour 3cm 15% KI grade 3 and some limited nodal involvement (had complete response from chemo). No oncotype as I had neoadjuvant chemo due to nodes.
I would have qualified for Abemaciclib and was due to start in January, but was worried about the side effects and QOL. Luckily I was able to access Ribociclib under my insurance. Apparently there is no or little difference in the effectiveness (ie chances of being alive at five years/recurrence) and therefore a no brainer for me to push for Ribo. However as mentioned above Ribo is available for patients with no nodal involvement unlike Abema so this is a massive change. You have to start Abema within three months of the end of treatment and Ribo within 12 months.
The studies are based on you taking one CDK 4/6 alongside an AI. The issue for me atm is the AI
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Just a quick update to say finally after 4 week break,my ALT is down to 79 and can restart ribo, albeit at 200mg. The 4 week break has also given my neutrophils a chance to recover. Felt tired with high ALT but no other symptoms.
Just wanted to post to say not to worry if you have to have treatment break, hopefully with time things settle and everything recovers.
Hope everyone ok.
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That’s good news x
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I thought you might find the below graph useful to show when you’re most at risk from infection
I’m on day 14 (red) and my neutrophils today are manageable but lower than two weeks ago (green phase). I didn’t appreciate that we are given the “week off” to allow our immunity to recover.
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Hi everybody - hope everyone is keeping well.
At last I have started again after nearly a six week break. ALTs reduced eventually and I have commenced on 400mg today 
And the sun is shining 
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Fantastic news. Pleased for you, all the best.
Another sunny day. Love to all
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Hi all, I feel a bit of a fraud posting on here but I have found the information useful. I have secondary breast cancer and have 600mg a day. My neutraphils are 1.2. The thing I suffer the most with as a terrible rash. I am on 5th dose of Ribo. Has anyone had the rash and it has gone on its own accord or did you have to reduce the dose.
Lee
Hi Pug, I just don’t understand the “to qualify for” bit in her email.