Letrozole hot flushes

Is there anything available to reduce the hot flushes whilst on Letrozole? They are horrendous and my face and neck are dripping wet when I have them. They are annoyingly often and I find them embarrassing and frustrating.

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Hello, I take a low dose of fluoxetine daily which got my flushes under control.
It treats anxiety but in the low doses it works for flushes.
Hope this helps.

An anti-depressant can help but so can gabapentin. I am on a anti-depressant and I’ve started having hot flashes recently but they’re very mild to the point that nobody notices but me.

I take fluoxetine too which helps flushes, i take one in the morning and letrozole at night with success.

Hi uniboob50

Thanks for posting.

It sounds as though you are having a difficult time with hot flushes since starting treatment with letrozole.

Hot flushes are the most commonly reported menopausal symptom due to breast cancer treatment and many women contact us describing the difficulties they are experiencing with them. The frequency and severity of them vary from person to person. For most women they will fade over time and become less severe, but for some they may continue to experience hot flushes which can really affect their quality of life.

We know that there are different things that help. You can speak with your breast care nurse or treatment team to discuss possible options for managing hot flushes. Your GP may also be able to help. You may want to ask about a referral to specialist menopause clinic where you can get further advice and information about coping with menopausal symptoms.

As @M0lly-Chorley, @kay0987 and @mazz1066 have all said there are also prescription drugs which, when taken in low doses, can help to control the hot flushes. You may wish to discuss this with your treatment team or GP. In the meantime, the following link to our booklet on menopausal symptoms and breast cancer has some further information you may find useful.

For many people, it’s not always ‘back to normal’ when they finish hospital treatment for primary breast cancer. Adapting to life after treatment can be difficult and often the need for information and support continues. Coping with the shock of a diagnosis, treatment and side effects, and worries about recurrence can make it difficult to readjust to everyday life again.

You may be interested in our resources that are particularly for those who have come to the end of their main hospital treatment. These are known as our Moving Forward services and include our Moving Forward booklet and Moving Forward courses.

The courses are open to people who have had a primary breast cancer diagnosis and have finished their hospital-based treatment within the last two years.

Through supportive, open conversations in a safe, confidential space, you’ll connect with people who understand. And you’ll find the tools you need to feel more empowered, confident and in control to begin to move forward with your life.

You can attend Moving Forward either at our face-to-face course or take part by joining online. Find a course near you or register for an online course via the links above or call us on 03457 077 1893.

Do call our helpline if you would like to talk this through or have any further questions. The helpline team have time to listen to your concerns, talk things through and signpost you to more support and information. Your call will be confidential, and the number is free from UK landlines and all mobile networks. The number is 0808 800 6000, (Relay UK - prefix 18001).

If you would prefer one of our nurses to call you. To do this, please complete this form ticking the box agreeing to a call back.

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We are closed on Monday the 28th August for the bank holiday.

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Best wishes


Breast Care Nurse

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