Letrozole, ibandronic acid/ zoledronic acid, ribociclib (kisqali) - tell me all about them

Hi all,

I’ve got 2 more chemo left then 20 radiotherapy.

I’m already on zolodex every month. They want me to start Letrozole after I finish chemo… I then need to decide between ibandronic acid or zoledronic acid. Then after radio they will put me on Ribociclib. I feel like I will rattle!!!

I know nothing about these so please tell me all you know. Side effects, recommended daily tablet or injection, is it right that ribociclib has only just been approved?

Thanks for all your amazing advice as always xx

If I had a choice I would choose zole infusion over ibandronic tablet. I am going to be put on the tablet.

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My undersanding is that Ribociclib has only just been approved in the last 12-18 months for prevention of progression to secondary but it has been used for secondary for longer. I’m currently on Letrozole and Zoladex but I actually have a follow up today with my oncologist and I’m going to be asking if I am a candidate to move to Ribo so I’ll be asking about side effects in comparion to Letrozole today. Im tolerating Letrozole and Zoladex pretty well. My main issue seems to be recurrent UTIs which have resulted in me getting a pelvic ultrasound to check that there wasn’t anything more going on (there isn’t so apparently I’m just going to have to learn to live with them :frowning: ) I’m going to be getting the results of my latest DEXA scan today too so I’ll be finding out if the bones are holding up ok or if I need to move to any of the bone injections so can’t help with that side of things but will be watching here for other responses to that x

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I’ve been on Letrozole for four months, and found it impacted my mobility, to the extent that every part of me felt arthritic and painful, and basic tasks like getting dressed required all sorts of strategies to accomplish. I looked back at my meds and realised I’d been dispensed a different brand of Letrozole every month, so have recently asked my pharmacist to stick to one brand, which seems to have much fewer side effects for me.

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