Hi @mun4o
Sorry to hear the oxybutynin didn’t work for you. Now 3 1/2 weeks and still getting flushes. 
but told to wait 4-6 weeks and was suggested could have double to dose.
The Veoza /Fezolinetant worked with a few days, it didn’t take the hot flushes away totally but the ones I did have were manageable. Yes it is quite cost prohibitive, with £250 initial consultation, then £150 for follow up every 3 months by phone and then the cost of the drug, pharmacy charges and postage costs. I have made it clear I want to go back on it as soon as it’s on the NHS. I had no side effects from it, whereas Oxybutynin is causing headaches and in the long term can cause glaucoma ( already have family history and yearly eye tests on the NHS, so don’t want to make it worse).
As far as trials, I don’t believe the published ones were specifically done with breast cancer patients but there is supposed to be one ongoing. I don’t believe all drugs are trialled specifically on breast cancer patients such as anti depressants prescribed for hot flushes. I took it that it had no hormones so it was safer than HRT (NICE preferred drug for flushes).
Let me know how you get on with Veoza if you decide to give it a go.
