Message for Jane RA

Hi Jane

You’ve answered a lot of my posts in the past, I used to use the forum loads but I’ve just been looking on the forum from time to time since. I’m intrigued about what you said to Eileen765 recently about triple neg being more likely to recur.

I’m neg hormones but her2+ so a bit different but I think it’s the hormone bit that’s important in all this recurrence. I was given a very poor prognosisis last Jan as 12 out of 15 nodes involved and it had spread into surrounding tissue.

I’m really interested in this, can you let me know a bit more? I know that you’ve done your research!

thankis jane

hannah

Hi Hannah

I don’t think I’ve ever said that triple negative bc is more likley to recur…well if I have I’m wrong!

What I may have said is that if trip neg is going to recur it is more likely than er+ and pr+ bc to return in the early years after treatment for primary bc. By the time trip negs get to 8 years some research shows recurrence is virtually unknown.

Her2 is very important in recurrence too with her2+ breast cancer being considered more aggressive than her2-, though herceptin has evened things out.

Triple negative breast canncer isn’t just one kind of breast cancer, but a shorthand term for any breast cancers whicha re er- pr- and her2-…there are several different types. High node involvement is a poor prognostic factor whatever type of breast cancer.

Where’s the post that you think I said trip neg is more likely to recur? I’ll correct it if thats what I’ve said.

best wishes

Jane

Hi Hannah,

I hope you don’t mind me butting in. Her2+ used to be worse than triple negative, but if you received herceptin, preferably with a taxane, the odds are now probably no worse. Hormone-receptor negative continues to be worse than hormone-receptor positive in the short term at least.

On the other hand, I had 8/19 lymph nodes involved after FEC chemo with vascular invasion and added risk factors and am still here five plus years later with no sign of disease. The big things to focus on are what you can do that might possibly help , such as getting the generally recommended amounts of fruit and veg and exercise and not putting on weight, since studies have found correlations between these things and survival. There was a study that linked an ultra-low fat diet with improved survival in hormone-receptor negative patients, but the level was unfortunately something that patients were told they could not achieve without a highly-skilled dietician. There is some suspicion that olive might be relatively beneficial for her2 patients (raises sensitivity of her2 cancer cells to herceptin in test tube studies) and some types of other oils (corn, other omega-six) fairly harmful for her2-patients. Unfortunately, the low-fat study did not look into the different types of fats but was conducted in the U.S., where omega-six fats are very common.