Thanks for replying. I actually found out my score is ready. I have an appointment tomorrow. I am really nervous about it. I am 42 so I believe the threshold for chemo is a bit lower.
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Fingers crossed you get below the 16 tomorrow
Will be thinking of you
Xx
Thanks for replying. I got it back and it was 17. They have recommended no chemo as they don’t think the benefit wouldn’t outweigh the risks. I would like to know peoples thoughts on this. I am pleased it wasn’t very high but I was hoping it would be lower - 17 feels like it is in a grey area .
Hi.
As you I am in the grey area, 48 y.o, 18mm IDC grade 3 ER100% PR 90% Ki67 40% ILV and Oncotype came back 16.
I was told this means around 1% benefit of chemo, so it was not recommended.
When I worry I try to tell myself that best I can do is to stick to my treatment.
I wish us all the best.
Thanks for replying. Mine was grade 2 , prostegeon +(7) estrogen(8) - I don’t know the percentages. Node negative and no LVI
My oncologist seemed to have completely ruled out chemotherapy. It didn’t even seem to be an option. I think I will just have to accept it and get on with the radiotherapy. But there is just a question hanging in my mind.
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Just to add my KI67 was 5-7 percent so I hoped my oncotype would be lower. I just wonder whether I should be considering something in addition
Hi again.
From what I understand Oncotype tells whether chemo will be beneficial or not for a particular tumor (based on their 21 genes). I thought RS will be higher than it was to be honest and told that to the Oncologyst as I worried about grade 3, high KI67 and ILV. He replied that that was why they requested the Oncotype test.
I am now waiting to start radiotherapy and taking tamoxifen.
I really wish the best for us all.
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This is good, as they say low KI67 has a better prognosis.
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I am starting radiotherapy in a week and Tamoxifen tomorrow. Complete second wanting the best for us all.
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That is fast! It is good news not having to wait longer.
Radiotherapy seems to be a bit delayed here.
I had the tattoos made last week and already using the Avéne Xeracalm cream twice a day.
I am just wondering how great my risk of recurrence is with an oncotype of 17 and whether my oncologist is right to rule out chemo. It would be great to hear more views
At the moment the plan is radiotherapy and Tamoxifen. I am just wondering if I should be offered ovarian suppression. Does anyone know what situations they offer this in
Hi I got my oncotype score today and I am feeling a disappointed. IMy score was 17 so intermediate. My oncologist hasn’t mentioned anything about ovarian suppression but I am wondering if it is something I should be considering. I am also highly er positive. Can I ask what your score was?
Just dropping in after a while, and wanted to say its good to see that you’ve received your oncotype score without delay and that it’s on the low side as anticipated earlier.
Regarding the score ranges, there’s a section in the Oncotype report under the sub-heading “Real World Evidence of SEER Registry Outcomes in Patients Treated Without CT Based on RS Results”, which outlines them as RS “0-10”, “11-15”, “16-20”, “21-25” & “26-100”. I think we all have a gut feeling of where we would like to fall before we get the result. That’s either under the highest score group if we’re mentally set for having Chemo, or the lowest score group if we are mentally against having it based on whatever internal measure we’ve used to get there. In my case I felt my score came back too low for my cancer profile, so had to work on mentally & emotionally adjusting to not having Chemo.
Personally I think you’ve got a great score, in combination with all the other known tumour profile characterises, not having Chemo would make sense.
Regarding your question about Ovarian function suppression, do ask your oncologist about that so that it’s clear why it is or isn’t in your treatment plan. Your oncologist would be following the NICE guidelines for this, which you can take a look at here, under section 1.7.4 & 17.5. They do have a paragraph explaining the rationale there as well.
Thanks so so much for your reply- this forum is inavuable. That guidance makes sense and is really helpful. I am going tohave a look at the oncotype info that you included too… I actually emailed my oncologists secretary and she replied saying she would discuss ovarian suppression at our next appointment since I had been on Tamoxifen for a while. She added there is a small benefit but can have side effects. I have a feeling it will b grey area for me and may depend how I get on with Tamoxifen.
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Hi , my score has come out as intermediate as well. . Can I ask how what factors led to decision to include Zoladex?
Hi thanks so much for your message . My Oncotype came back as 17also intermediate.
Can I ask what yours was? How did you make the decision to do the ovarian suppression as this is something that makes me feel nervous. My oncologist hasn’t mentioned it byet.
Before I had the test done, my oncologist told me expects a low score based on my profile. Luckily, I had a 14 and no chemo. That was 2 years ago and I’ve had good follow-ups, including my last one on Jan 22. There are so many factors, I wouldn’t attempt to recommend either way. Good luck.