Side effects of Tamoxifen compared to Letrozole

Hi ann-m

I’ve also been on Tamoxifen for 2 years and am due to switch to Letrozole soon for a further 3 years. I know some people get bad side affects but for me the Tamoxifen has been absolutely fine. Joint stiffness and hair thinning initially but it settled down. I’m really worried about switching as Tamoxifen seems to suit me. I’ll soon be 57 and wasn’t quite through menopause when I started on it. Now I’m certainly post menopause I probably need to switch to Letrozole
but I’m very apprehensive about it.

Hi I started Letrozole last March but had all the side effects many have stated - brain fog. vaginal dryness & awful pains in joints.
I switched to Tamoxifen in September and all of those things resolved. Yes I still have sleep problems & hot flushes but overall I feel so much better.
My consultant was wonderful & listened to all my woes so talk to the clinic and see about swapping ?

Just today switching from Letrozole (on it 1 1/2 months and side effects daunting).
Convinced ONC to switch me to Tamoxifen.
I HOPE it has less side effects.

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I am 76 and have been told I will be put on Tamoxifen, but do not want to take it because of of all the side effects. It’s a dilemma, so I am trying to get opinions how people went on who decided not to take it.

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