Afternoon, I have been on Tamoxifen for 10 months and I have recently been diagnosed with pre-diabetes. My bloods pre Tamoxifen were fine. I have done a bit of research and seems there is a higher risk with Tamoxifen.
Anyone had any experience of this? I’m wondering if they would change me from Tamoxifen to an AI and potentially suppress my ovaries. I am pre-menopause.
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Hi , same thing happened to me the first year I was on tamoxifen! My bloods came back prediabetic! I also did research and read that could be the case. I have been taking it nearly 5 years now so hopefully after I stop bloods my go back to normal.
Seems a strange coincidence
Hi, thanks for replying. That is really interesting. Out of interest did you speak to your oncologist about it?
Hi @loobylou25,
Thanks for posting.
Tamoxifen has several side effects but a higher risk of developing diabetes is not listed as one of these. There is no mention of this on the manufacturer’s website either.
There are some studies which seem to suggest that there may be a slight increase in developing diabetes in older women, but that this needs further research. Although @sparkle0103 has responded to your query having had a similar experience, this may be a coincidence.
You mention that you are pre-menopausal and are wondering if changing to an aromatase inhibitor (AI) alongside ovarian suppression may help with pre-diabetes. The best people to ask about this would be your treatment team, and whether it would be clinically appropriate for you.
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