My mum has BC young not sure age she was diagnosed but died from it at 34. Her mum my Nan died from Overian cancer I think at 61 my nan was one of 8 girls a number of them had ovarian cancer.
I was checked for genes about 15 years ago but nothing showed Brac negative. I was supposed to have mri from age 30 but when I reached 30 was told wait until 35 then I never got called up so chased them at 37 had my first MRI and there it was already. I now had BC
I was referred back to genetics who run more tests against I think about 36 known mutations and still nothing. They said they will offer treatments as if I was found positive as such a strong link and they will re-test every 5 years and see if it has been identified yet they learn of new ones all the time.
I have had double mastectomy cancer side and preventative other side and overies removes. I have a twin sister she has had double mastectomy as we have same DNA and my younger sister of 4 years has had preventative double mastectomy. They will look into overies but once they are 40.
I have just joined, so sorry it's a year on!
I was told my breast cancer was oestrogen related but then after negative BRCA 1 and 2 testing, I have recently found out i have the PALB2 gene , might be worth requesting this testing??
When my Mum was diagnosed 18 years ago she had the genetic test and the Brca genes were not found, as my aunt (her sisster now has it) she will be tested as well. I have a docs app in a couple of weeks and i am going to ask to be referred to the genetic clinic- my mum went to guys and st thomas in london. I am hoping that the genetic tests will have improved in the last 18 years and we can find out what is going on! In the mean time, i will request annual MRI's and mammograms and anything else they can offer me.
The types of breast cancer within our family seem to be oestrogen related. Perhaps there isnt a genetic link as such but we just all have high hormone levels? Im not sure if that could be a possibility?
Oh yes of course that is something to consider with the preventative surgery that it may cause issues for the next generation- i have two daughers...gosh it is a mine filed!
So do MRI scans show up more than mamograms? Can they detect things sooner?
All on my mothers side of the family...My mother had bc at 46, my aunt at 59, my grandmother at 41 (she had two primary's breast and bowl) and great aunt at 88 (i realise this is very old and may not be as relevant to family history).
My aunt was just diagnosed a couple of weeks ago- so she will have the genetic tests done and i guess we will all take it from there.
Hi , yes you should be offered the masectomy with a family history even without the gene. My mam and her 3 sisters had BC 3 sisters died mam had a masectomy. Its now making its way threw my generation with no gene been found, my 2 cousins had masectomy after lumps been found, 1 cousin is dying. We get a mamogram an MRI and an examination from the breast surgeon every year. I am now 48yrs and had a biopsy 5weeks ago after 2 lumps being found after my MRI , they are inconclusive so now its a wait for an appointment for my core biopsy, letter says it could be ATYPICAL AREA, anyone had this???