I was tested for BRCA1, BRCA2 and TP53, all of which came back clear. My genetic councellor wasn't happy to leave it there as I had had breast cancer and also my mum and grandmother.
I was diagnosed with CHEK2, which is also a mutated cancer suppresent. I now have yearly scans for thyroid, kidney and colonoscopies every 3 years. I have also had a full hysterectomy as a preventive surgery.
It is such alot to take in, I hope you get the answers you want.
Sorry for not replying before but I haven't been on here for awhile.
Best wishes xx
Thanks for that, I have only had breast cancer in my family and none of the others, I also have no history of childhood cancers and thats what im clinging on too. Who did you email? I have been told I have around a 3% chance that I have this gene, not high I know but I probably have it as its just my luck! I am so worried and I really dont know what to do for the best, i am only 23 and i dont know if I can go on for years knowing that I will get these other cancers!
I got tested for the TP53 gene and am negative. If you do have it, as you say, you are at risk for other types of cancer. It is a big decision whether to have the test or not. Ignorance would allow you to live your life to the full without having to constantly worry about developing cancer. On the other hand, if you know you have a faulty gene, you will get far more screening done to detect cancer at an early stage. The TP53 gene runs in families so are there many cases of different types of cancer within your family, not just breast cancer? I did have a few types of cancer within my family, but not really enough to warrant a diagnosis of faulty TP53 gene. I did actually email a professor who runs clinical trials on Li Fraumeni syndrome and she was fairly certain I didnt have the gene even before the results came back. I think sometimes the geneticists will test even though you don't fulfill the criteria causing lots of undue stress.
I have been to the genetic hospital today and they said that after finding out that i havnt got either BRAC1 or BRAC2 gene that I may have a gene called TP53. Apparantly this is a really bad gene and gives all different other cancers. I dont know if to have this test as im not sure that I want to know if I have this gene. I had BC last year at the age of 22 and not sure if I want to know that im gona get brain cancer, leucemia, bone cancer or muscle cancer. I want to live my life a little bit. Im sooo worried.