Just joining the debate on Letrazole, I started beginning of April with TEVA brand and had the expected joint and muscle pains which have been manageable. Then one month I had Accord brand and within a week my hands were so stiff and painful so talked to the pharmacist who exchanged them for TEVA . Next suggestion was it try Actavis but apparently that company has now been taken over by Accord so what will happen to the Letrozole, will it be the Actavis or Accord version?
I have requested a month of Femara to see if there is a difference but GP very reluctant due to the cost so has suggested another brand Advantage first.
For the last month I have developed a right trigger thumb which seems to be fairly common as well.
If I am to take this for the next 5 years I really want to have as few side effects as p[ossible. I guess the problem is we are all so different and its a matter of trial and error, even my Oncologist has suggested working my way through the different brands!!
Hi everyone. I have been reading your posts ever since I was diagnosed in May. I have responded to a couple and sent hugs but so far have had little to say as my treatment has gone really well. I was put on a trial of hormone treatment including letrozole to shrink a stage 2 23mm tumour. Over 14weeks it has shrunk to 10mm and I've felt fine on Dr Reddy's Letrozole from hospital. Thanks to you lovely ladies I was fully aware that there are other brands and that they can cause havoc. So last Tuesday when the trial ended and the hospital said I now have letrozole from my GP the battle began. I have surgery on the 23rd of October so staying on the same brand was important to me as I have been fairly well. The GP agreed, then called later that evening to say no go on Sandoz. I asked to speak to another GP he was really arrogant and tried to say thet all brands were the same. Thanks to this forum i know that is rubbish and told him so. After what turned out to be a heated discussion he admitted Dr Reddy's were too expensive but gave me a prescription for one month to get me through surgery. I have now been told Dr Reddy's is made in India and has been withdrawn from the market due to poor quality control. So back to square one. Last night I took the first Sandoz and hot flushes kept me awake and I'm suffering again this morning. I am scared to find out what comes next. Sorry for such a long rant. I know I have been lucky so far. Love and hugs to you all. X
Hi, I switched from Actavis Letrozole to the Accord brand about six months or so ago.I was on Cipla for about a year . I find it hard to believe that there is a difference between the brands but it seems to be the case. I wonder if time comes into the equation as well. It has been 2 years 4 months since I started Letrozole. I sleep quite well , probably because I get very tired these days. I seem to have got a bit of my 'mojo' back recently and am a bit more motivated to do things.
When I first started Letrozole I had very heavy sweats in the night, absolutely drenched .They stopped as suddenly as they started after about six weeks. I feel that maybe the body settles down a bit in time although I realise that younger ladies may have more symptoms as they have more oestrogen in their bodies to start with. I was 62 so well past the menopause.
A lot of ladies have switched from the Cipla brand so maybe that is something you could try .
All the best
A few months ago I changed from Cipla to Actavis, I feel it is a bit better and my hair loss is minimal now.
I was on Cipla for a year so gave it a good shot, I read on here that actavis was one of the most similar make up to Femara. I do find that if I get a very ' creaky' achy day that a couple of ibroprofen in the morning make such a difference and I am absolutely fine for the whole day. I don't take them every day.
My day has a very slow start just like yours, priorities change hugely don't they!
Are you on adcal as well as cod liver oil?
I have been on Letrozole since July 2015 and I remember getting throbbing pains in my feet and ankles which was helped by rubbing them.
It doesn't happen now unless I have a very heavy day. I also woke with very heavy night sweats but these stopped as suddenly as they started after about six weeks.
I feel that I can cope with the side effects that I do get.....stiff joints etc if I and my family lower expections on myself. I am 63 and am lucky in that I don't have to work. I really feel for the younger ladies with families to care for who might find it more difficult to cope with any side effects.
I look after the grandchildren sometimes but am finding it a bit of a struggle. I do not want to tell my son and daughter that I can't cope but I do get rather tired.
I take glucosamine and adcal d3.
I don't take cod liver oil as I wondered if I would be getting too much vit d. I keep meaning to ask a doctor if I should or not. Perhaps someone on here has got the answer to that question.
I take my tablet just before I go to sleep, when do you take yours? I wonder if taking it at night means that I sleep through some of the immediate side effects i.e. Nausea etc.
I do not experience constipation.....more the opposite!
I actually think I sleep better on Letrozole than before or maybe I just get more tired.
I have to agree with the ladies that say exercise helps but sometimes it is a struggle to get motivated...it is usually worth it though.
All the best to everybody
I started Letrozole Teva only 5 DAYS ago and the muscle pain is terrible. I am also nauseous and constipated. I hope this subsides. I started Cod Liver Oil tabs. Any other suggestions.
I agree with you that the side effects of Actavis seem to be less than cipla, I started Actavis Letrozole a month ago and feel much better, my local branch of Boots seem fine about getting it for me although a year ago I was automatically given Cipla.
My legs do not feel so stiff and sluggish and lately I feel that there is a lot of time now that I almost feel 'normal' again!
All the best
I think it is highly individual how we all react to the different brands. I was fine on Cipla but then got Actavis for a couple of months and got a return of joint pains which only went away when I got back on Cipla. I find the best ones for me are Sun Pharma and Accord which I feel fine on. Cipla is okay but I don't have any allergies so maybe that is why. I have given up arguing with chemists and GPs about how different brands affect me as they all look me straight in the eye and tell me there is no difference.
Hi there, just to say I did some research on the different brands because I was initially dispensed with Femera from the hospital and then dispensed Cipla from the local pharmacy. Side effects from Cipla can be the same as the active ingredient of Letrozole, so a double whammy, this is because of the ingredient Tartrazine used in the coating for Cipla. The closest to Femera are Sandoz, Zentiva and Actavis. Sandoz is unlikely to be dispensed because costs are pretty similar to Femera, however, my high street pharmacy have been able to order in Actavis despite having Cipla available. I have only minor SEs on Actavis whereas on Cipla the SEs were getting worse. Hope this helps.
I changed my Letrozole a month ago from cipla to actavis, I think I feel a bit better.
I read somewhere , maybe on the forum that it is one of the most similar to femara.
I was on cipla for a year so feel I gave it a good try. I also read recently that somebody felt that cipla wasn't so good for the hair.
I don't think my joints ache so much and don't feel so stiff.
All the best
Hi ladies I'm at that point this afternoon where I don't know whether to be angry or cry the latter I think I am struggling with letrozole and joint pain especially shoulder at the moment I started on cipla brand which was horrible currently I'm on accord which is no better my usual pharmacist was away so I saw another one who in a nutshell said they are all the same doesn't make any difference which brand it's not the brand it's the actual letrozole that's causing the problems I don't agree because some ladies have changed brands and been better my next question to him was the pure brand femera he basically said unless you are allergic to any of the other brands then it is highly unlikely it will be prescribed because of the cost unless I pay for them myself any suggestions ladies I'm so fed up love Judi.