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Ibrance & Letrozole


Re: Ibrance & Letrozole


I’ve been on Ibrance (Palbociclib) and Letrozole since last December.  I have Secondary Breast Cancer in the Bones. On the whole I have found it to be a very manageable treatment plan.  With Ibrance I started off on the highest dose of 125mg but after two cycles I went on the 100mg dose and for the past few cycles, I am on  the lowest dose of 75mg.  Every month you are required to have a blood test and from the beginning even until my last cycle (treatment) I have low neutrophils as the Ibrance affects your white blood count (WBC). Most hospitals expect a count of at least 1 to enable the cycle to happen and for me, it is a struggle to reach that 🥴.  Since my Primary diagnosis and treatment over 15 years’ ago, I have been left with low energy levels and probably have undiagnosed Chronic Fatigue so it might just be me (some women work full time through taking Ibrance and Letrozole) but I do have days where I sleep for hours.

Very best wishes to you and my advice would be to go for it, jump in and see how your own personal journey with these tablets goes.






Ibrance & Letrozole

Hi Ladies, I’m new to the group and would like to know your experience on Ibrance & Letrozole?