Hi, I have been taking anastozole for 5 weeks and just this week I have started to feel shooting pains in the inside hinge of my elbow. there doesn't seem to be a weight trigger just randomly, when I lif my fore arm, eg to put in an earring, the shooting pain makes me gast. What is the general consensus? could this be from the anastozloe? has anyone had the same thing? Does itget worse? I would so much appreciate any feedback I can get, Thanks, Rachel
Just about to start on anastrozole, after surgery and TC + Herceptin. I already take pain meds for existing long standing problems. For nerve damage, I have 10/20mg of amitriptyline at night, and for bone pains, I have 60mg of nefapam 3 xday. I hope this does the trick for any extra joint pains as I can't have any anti inflammatory drugs due to previous existing renal issues.
I visited this site for the first time this morning while researching Anastrazole (Arimidex generic). I was amazed to see your post. I too, thought I was doing well, until the joint pain kicked in. I have been taking Naproxen but to little relief.
Please let me know how things work for you.
I've not visited this site for some time and have just found this thread. I have been on anastrazole since January and smuggly thought I was doing quite well until last week when the painful joints kicked in. GP has already put be naproxen + omeprazole as we assumed increased knee pain was wear and tear but now have random joint pains and a trigger finger.Trying paracetemol before going back to GP. Wine and gin work wonders but the liver might object to that longterm lol.
Acupunturevis awesome and really works, but INS will only cover 5 a year and breast cancer sites recommend one a week..
I've been wondering how you have been getting along since I last heard from you on the Forum. So sorry to hear you are having really bad joint pain at night. It is awful when you can't escape the pain as you lie in bed trying to get to sleep.
I am allergic to Ibruprofen, Codeine, Tramadol, anti-inflammatories etc. therefore suffered terrible pain for many months until my GP found an alternative medication that helped to reduce my pain. She prescribed Amitriptyline (for neuropathic pain) which is given in low doses. At first I took 10mg at night but the pain was still at a severe level so she increased the dose to 20mg which helped. However, I found that 25mg was the strength that gave me the best relief from pain which enabled me to have a better night's sleep. I've heard from other ladies on the Forum who have taken it for pain relief and Amitriptyline worked for them too. Some got pain relief with 20mg, it depends how you react to it.
My pain has not gone completely but compared to how severe/unbearable it was, Amitriptyline has been a life saver for me. It does make me feel sleepy after taking it at night before bedtime but that's fine by me because I want to sleep and not lie awake most of the night feeling pain.
Cils, Tamoxifen frightened me too! I had a terrible reaction to it. Awful cramps in my legs, body overheating to an alarming degree and the dull period like pain you described. I was relieved when the oncologist switched me to Anastrozole because the possibility of having a DVT, stroke or womb cancer scared the living day lights out of me. I just felt weird on Tamoxifen. The medical scientists have proved Tamoxifen is not as good as Anastrozole so I would rather take Anastrozole to prevent a recurrence.
How are your eyes?
I had my right eye cataract removed five weeks ago and everything has healed fine. At least, both my eyes are OK now. No longer have to live with cataracts and poor eyesight.
Wanted to tell you that I made a mistake about the tiny pellet the nurses put into my eye prior to surgery. The tiny pellet is to dilate your pupil (some hospitals use dilating eye drops). The local anaesthetic is put into your eye (via eye drops) by the surgeon in the operating theatre. Sorry for making this mistake Cils, I got confused and wanted to let you know.
Take care and maybe ask your GP if you could try Amitriptyline to help with the night pain. It's worth a try and if it doesn't work you can always stop taking it.
hi magical moon
i too am suffering real bad joint pains and seems more so at night.even when you lie on your side it seems to be compresing my joints together. im up now at 12.05 in the morning typing this for comfort.I have taken ibroprofen to see if helps.what did your doctor recomend to help you with this problem?
I stopped taking anastrozole and took tamifexin and i had very strong dull pain like period pain , it frightened me so after 8 tablets i stopped (thinking of womb cancer). Back on anastrozole.
please let me know your thoughts and anyone else too , so glad of this site
From my experience, up to the six months marker the pain had reached the highest level and was constant both day and night in all my joints. It was unbearable and dominated my life.
I have suffered from severe migraines most of my life and always considered myself to have a high pain threshold. But living with chronic joint pain daily wears you down. If my GP had not found a solution to reduce the severity of my pain, I would not have been able to persevere with taking Anastrozole.
If you have been taking Anastrozole for five months, I would think that your side effects will have reached their maximum now.
Hope you can find a solution to ease your joint pain.
Very best wishes.
Hi have now been on anastrozole 5 months and joint pain has definitely increased. Struggling to go at the same pace as I used to but definitely better to keep moving. Now getting pain at night as well. Who would thing turning off the oestrogen would have such an effect! Does the joint pain worsen the amount of time you're on Anastrozole, as still a long way to go?
I was diagnosed with breast cancer late October, with lumpectomy, and SAVI brachytherapy in November and December. Due to my mother's exposure to DES drug during her pregnancy with me, both of us got breast cancer, so anastrozole was recommended. Very few side effects during the first 3-4 months, but now I am hurting. Severe pain in right wrist and fingers, and right ankle site of a previous sprained ankle. Waking me up at night. I'm too young (relatively speaking) to feel this crappy. Can anyone tell me if it is worth it? Without meds supposed to have 80% chance of "freedom from cancer" with med 90%.
Hello again Magical Moon, thanks so much for your informative reply. It does help somewhat knowing other people are going through the same problems. I think many of us are stuck between a rock and a hard place with these drugs.
My allred score was the same as yours so I know it makes sense to carry on with Arimidex but my body is shouting STOP!! Well done you for carrying on, I admire your tenacity! I will plod on for now and hope that symptoms will improve.
Thanks again for replying and the hug!
I have been on Anastrozole for about two years and I too enjoy keeping fit. I had been experiencing a great deal of repetitive pain in my wrist, inside my elbow and my arm generally but then I stopped trying to include lifting small hand weights during my daily exercise routine and it made a huge difference because I don't have any pain whatsoever now. I am convinced that using even tiny weights was aggraving the problem. I am also careful to avoid carrying heavy shopping bags too.
Sorry to hear you have been having unbearable joint pain. Even though we know we have to take Anastrozole to reduce the risks of having a recurrence, it does seem unfair that some of us are burdened with awful side effects.
I struggled for about seven months with severe joint pain every day where pain dominated every minute. I normally have a high pain threshold but when it was constant I found it unbearable. My sleep was disrupted through the pain (woke up every two hours).
My GP prescribed me various codeine based drugs to find a solution but none worked, they just gave me severe migraine. Unfortunately, I am allergic to anti-inflammatories (e.g Voltarol, Ibruprofen) and most strong painkillers (Tramadol, Co-Codamol, Co-dydramol etc.) I didn't want to try Morphine because of my allergy to opioid drugs.
After seven months of trial and error, I switched to another GP in the practice. At last, she was able to help me. I was prescribed a low dose of Amitriptyline (used for neuropathic pain). Started at 10mg, then increased to 20mg and finally found that a dose of 25mg helped to reduce my severe joint pain. For the first time in ages, I was able to sleep for four hours before waking up. A miracle.
Amitriptyline has been a life saver for me. My joint pain has not gone completely but the intensity of pain has reduced by some degree and now I only feel pain when I move. Before all my joints ached badly even when sitting still of lying down.
I've been taking hormone therapy for two and half years now and Amitriptyline has definitely helped me to remain on Anastrozole.
There was a recent thread about Amitriptyline, here is the link.
Good luck finding something to relieve your pain.
I was diagnose January 14, 2015 and I've been taking anastrozole since October 2015 before that it was raxifene but I couldn't take that anymore the side affects were too much. My joint pain is sometimes unbearable with anastrozole but I know I need to continue to take it.
I execise two to three times a week and it does work but nothing can touch the pain during the night sometimes.
Any suggestions for joint pain?
Hello Christine (Rubycat),
Fantastic news about your all clear, NED result.
Plus, many congratulations on your amazing achievement with weight loss. That must make you feel very proud of yourself. A fantastic result.
Peace and Positivity,
Good to hear that you had a positive result when you saw your oncologist. Thanks for joining the thread. The more the merrier.
I've gained weight too since taking Anastrozole mainly because I am less active due to my chronic joint pain. It's really irritating how a tiny, white,1mg pill can cause havoc with your energy levels and waist line.
The only advice I would offer is to be kind to yourself because your body is now having to function with hardly any oestrogen floating around your system. Our bodies are super sensitive and finely balanced and they've had a huge shock. It is a big ask expecting any oestrogen deprived lady to go pumping iron at the gym. How would a man feel if he was deprived of testosterone?
I'm a 100% certain that if I could take HRT again, I would be bouncing around like Tigger the Tiger with a downsized body. If only! Such happy memories of HRT and a body topped up with oestrogen.
Thanks for joining this thread and a warm welcome to you.
Yes, you are right. Anastrozole is mainly given at 1mg per day. Like you say, it is one dose fits all. However, this recommended dosage has been proven (through significant clinical trials including the ATAC trial) to be very effective at preventing BC recurrence. I've found hardly any scientific research information advocating a lower dose, such as 0.5 mg but have seen reference to a 10mg dose.
As you have already taken Letrozole for two months before Anastrozole, the only other alternative aromatase inhibitor you could try is Exemestane. This second generation aromatase inhibitor is different to Anastrozole and Letrozole (both non-steroidal and reversible) because it is a steroidal drug and the aromatase inhibiting mechanism is 'irreversible'. You may be interested in trying it before stopping your hormone therapy altogether but it could cause the same side effects. I was offered the switch to Exemestane when I was thinking of stopping Anastrozole but didn't because of the drug's 'irreversible' and steroidal properties.
Not quite sure why you would consider having oestrogen levels checked?
You have been taking aromatase inhibitors for five months, therefore your oestrogen levels will have already been significantly reduced. From what I have found out, the scientific evidence says that with the recommended daily dose of Anastrozole 1mg, estradiol is reduced by approx. 70% within 24 hours and by approx. 80% after 14 days of daily dosing. This percentage has been quoted even higher in some scientific articles stating that aromatase inhibitors can reduce circulating oestrogen by about 98%. (Yikes! No wonder all my joints are stiff and painful).
Unless you stop taking Anastrozole until your body is 'clean' of Anastrozole, having your oestrogen levels checked now would seem inappropriate.
Do you know what your Allred score(ER+) was at diagnosis? Mine was ER+ 8/8 which is why I continue to take Anastrozole despite the chronic joint pain. I've now got a mere 2.5 years remaining on my 'Anastrozole sentence'. (Sigh!)
The higher your ER+ score the more beneficial hormone therapy.
Must admit, I really struggled on Anastrozole for the first seven months and even asked my breast surgeon could I stop because the joint pain was unbearable. At the time she encouraged me to continue taking it for at least two years because this was the most critical time when a recurrence could happen. This made me too scared to stop.
It is a very personal decision whether to stop. I still haven't found the courage to quit my hormone therapy. My body wants to stop but psychologically I still need my 'comfort blanket'.
Take care and keep plodding on until you know what's right for you.
Hello 4th sis - yes, agree that this site is fantastic. Well done for the all clear - it's a great feeling isn't it - I had my all clear first mammo letter yesterday. I've found anastrozole really hard to lose weight with - prior to my surgery last year I had been with Slimming World and lost over 6stone easily within a year. After surgery it took me well over a year to lose the remaining 2 stone - it was really difficult. Slimming World is great, but it really is just healthy eating - but I do believe taking the AIs make it much harder to shift the weight. Good luck in whatever you decide to do. Christine xxx
Hello BrendaB, sorry you're having joint pain too. I've been on anastrozole since last July - and have really found that different brands have provided hugely different bone aches. Started on Accord, that was ok, then chemist supplied Teva, which got worse and worse with constant back ache and leg pains. I also have osteopenia, so taking Adcal D3. Now had a couple of weeks on Zentiva brand and WOW, WHAT A DIFFERENCE - even better than the Accord brand. Although still slightly achy on getting up, (in morning, or from sitting) that soon disappears and I feel PAIN FREE and can walk about with no aches and pains (haven't tried running yet - not fond of too much exertion!) Have you tried different brands for a month - anything is worth a try isn't it when these bone aches can floor you? Christine xxx
Hi Magical Moon, this is my first forum post so hello everyone! I am having awful side effects from Anastrozole. I was on Letrozole for two months post lumpectomy, chemo and radiotherapy then switched to Anastrozole which I have been taking for three months.
I, like yourself, believe that some people are much more sensitive to oestrogen deprivation than others and looks like I am one of those. Am I right in saying that there is only one dosage for this drug? It's as if one dose fits all and this just dosn't seem right at as we are all different. I wonder if it would be worth having my oestrogen levels checked?
I read somewhere recently than more than half the patients on aromatase inhibitors stop taking it before their alloted time and I can well see why. Must admit I am seriously thinking of stopping the drug and taking my chances but the thought is so scary and I am plodding on for now.
I'm so happy to have found this site!
It's been 18 months since I was de-lumped. I went to my oncologist yesterday and all is good (thank God) but these pills! Ugh! Before BC, I was a gym rat and proud of my strength - but it's been so hard to get back to it. I really thought after going through all of this crap that I would have a new lease on life but instead I find myself making excuses and just plain feeling worn out! I should probably add that I've gained 16lbs since the surgery. Any advice would be welcome!
Welcome to this thread. Feel free to have a rant anytime. It's good to express your true feelings about living with joint pain. All of us here can empathise because we have bad joint pain too thanks to Anastrozole. It really sucks having to take this hormone therapy when it gives awful side effects. But if it keeps Mr BC Nasty from returning, we just have to get on with it and have a rant every now and then.
What a relife to realize its not just me having the joint pain, i can cope with the rest but the joint pain is really bad. I'm 43 and feel like im 70, my mates just smile, i guess they dont understant truely what its like and think i'm boring cos i dont want to go to the pub after work. I'm knackered thats why, yes i say i'm ok but only because its difficult to explain how painful it can be. if i sit for more than 10mins i seaze up!!!.
i have read some of the other comments and i am on the teva brand too and my surgeon said well dont take them too.Its so confusing of what to do for the best.My doctor has written to the surgeon to ask advice too, if the doc dont know then how am i supposed to know Grrrrrrrrr
Hi everyone i'm lisa aka Bigbird, got BC in sept, op nov, anostrazole for 5mth
From my pathology report, my breast cancer was a very rare 'pure special type' (90% special components) Invasive Micropapillary Ductal Carcinoma. When researching for more information, I found that this particular sub-type of Invasive Ductal Cancer is very aggressive with a high rate of spreading to the lymph nodes and vascular system.
Both my breast surgeon and oncologist reassured me that, even though I had a very rare type of invasive cancer, the treatment was no different to any of the others breast cancers. Luckily, my BC cancer was early stage, Grade 2, no lymph nodes affected, so had lumpectomy, radiotherapy and have been given hormone therapy for five years (Anastrozole).
My understanding is that being ER+ is definitely a bonus, mainly because you can be treated with hormone therapy which helps stop any potential BC cells feeding off oestrogen. Reducing oestrogen and stopping BC cells from growing improves your prognosis, but a good prognosis is also dependent other factors too. The key ones being, the size/grade/stage of the tumour when first diagnosed and if it had spread to lymph nodes.
I don't think it is that straight forward removing both breasts to get a better prognosis, especially if the other breast doesn't have signs of BC. My breast surgeon was very much for breast conserving surgery if circumstances were favourable, and she would not have recommended removal of a healthy 'opposite' breast. That is why the majority of ladies are given hormone therapy to prevent a recurrence and also to help reduce the chances of a primary breast cancer in the other breast.
The circumstances where ladies have both breasts removed to improve their prognosis (where one may not have BC) is when there is a family history of the BRCA1 or BRCA2 gene.
Magical Moon...what was your diagnosis? what steps did you take to become breast cancer free? Is it true that if you are her2 negative and estrogen positive that your prognosis is good? Is it also true that if you have breast cancer in one breast that it is better to have both removed?
Congratulations on your imminent retirement.
I think the less stress you have the more you are able to cope with intermittent pain. You have more time and space to listen to your body and do pleasant things to relax. Time to find alternative ways to help with the pain eg. Yoga classes, Pilates, or just a gentle stroll in the fresh air.
Teaching is a demanding job and having pain at work must add to the stress.
Enjoy your retirement and your new freedom.
Peace and Positivity,
Hey Magical Moon...love the name.
Thanks for letting me vent. I'm feeling much better but don't know why. I am so empathetic to others who are cancer survivors. I love this forum and enjoy reading how others are doing as well.
I do have one question: I will be retiring in a month (teacher 25 years). Do you think that not working will alleviate some of the stress and intermittent pain? Anyone?
Welcome to the Forum and congratulations on being BC FREE for almost four years! Fantastic news.
Sorry to hear that you have started to get unpleasant side effects. It's no fun, as many of us here would agree.
Feel free to have a vent. It does everyone good to have one especially with ladies who know exactly how you must be feeling.
Pleased you joined this thread. Post whenever you feel like it.
Sending you a big hug.
I will be breast cancer free 4 years in May of this year. I have been taking the Arimidex for three years. Until now, I will doing okay. But for the last three months, I've been having strange ankle, lower leg, inside thigh and wrist cramps that are horrendous. I am happy to have found this forum. I cried as I read your words realizing that we share so many of the same symptoms. It's actually a relief. I paced the hallway last night three separate times because my body became so rigid. Scary stuff. I was not happy when I woke up this morning because the cramping is still here though intermittent. Whether I walk 30-60 min a day or not, I have the same seize up nights. Thanks for letting me vent.
Hi magical moon ,
thank you so much for your reply your layout of questions and answers are very percise and methodical to the point which i like and clear and understanding.you have enlightened me to questions i did not know and helps me to understand what to expect.
It is nice to know someone who has experienced some thing i might have to have.(will have) in the near distant future .
It is true then that you can get cateracts from taking anastrozole(aremidex)?
Just another thing we have to go through and cant get out of it.
my vision in left eye is slightly more blurry in long sight than the right ,if i put my hand over my right eye glass for reading the left eye is blurred or slightly blurred writing.only had eye test and new prescription 2 months ago.
suppose the eye sight will go both long sight and short sight at the same time?
as you say if you got cateract in eye already it will get worse gosh not looking forward to it at all.
at least its something they can fix.
take care magical moon will speak soon xx
The thought of having surgery on your eye is scary. I was very anxious but, now I have had my first eye done, I can reassure you that it is a very speedy, painless operation.
How long was op?
Only 10 minutes. It was incredibly fast, I asked the nurse to time it for me.
Did it hurt?
No. There is no pain. You are aware of something pressing on your eye intermittently which is caused by the small surgical equipment used to hold back your eyelids.
Will it grow back?
No. The cataract is the clouding within your natural eye lens. During the operation your natural 'clouded' lens is removed from the lens capsule inside your eye and replaced with a new artificial lens implant. The artificial lens implant will not develop another cataract. However, sometimes the natural lens capsule can become clouded a few months or years later. The risk of this happening is 1 in 10 patients but it is easily rectified by a simple laser procedure to correct it.
How was it when surgeon was attending to your eye (scary)?
Yes, I was scared when I laid back in the operating chair because I didn't know what to expect and was hoping the anaesthetic had worked. However, the whole procedure took no longer than 15 minutes. Part of this time (5 minutes) was used to clean around my eye with antiseptic solution and place a sterile sheet over my face. There is a gap in the sheet over the eye being operated on. The other eye is covered up. A fan placed underneath the sheet blows cool air over your face.
The best advice I can give for during the operation is to concentrate your mind on looking at the swirling, coloured lights you can see. You CANNOT see any instruments the surgeon is using or feel them touch your eye. Everything is blurred because of the local anaesthetic and also from the sterile liquid which is swished into your eye. The liquid causes the swirling lights effect.
DO NOT think about what the surgeon is doing. I did for a fleeting second and it was scary and a huge mistake. Think of lying on a beach, looking at the swirling lights, George Clooney, eating your favourite chocolate, etc. Just about anything but NOT what the surgeon is doing to your eye!
How did they freeze the eye?
A tiny pellet (the size of a grain of rice) was placed inside the lower lid of my eye. This contained the local anaesthetic and the nurse put the pellet in about an hour before the operation.
Can you see much clearer?
Yes, within 24 hours your vision comes back well enough to get around. Colours are much brighter. I had to wear my sunglasses the following morning because the light was too bright. Although the lens implant has a distance vision prescription suited to your specific eye measurements, I still need an additional prescription glasses lens to get 20/20 vision because of the shape of my cornea. You have to wait six weeks post surgery before having an eye test if you need glasses.
How bad had it become before I had cataract surgery?
My cataract was very fast growing. My ophthalmologist found the early stages of one in my left eye in December 2014. Six months later (August 2015), it was much worse. By then, I had double vision and very poor visual acuity which could not be corrected by wearing a prescription lens. My balance was affected because I could only see clearly with one eye. I felt unsteady as if I was falling over which made me feel sick and dizzy. Going down stairs/steps was awful.
When the symptoms get so bad to affect your day to day living, driving etc. your ophthalmologist will be able to refer you for cataract surgery.
Cilla, I agree it is another hurdle to go through but it is such a relief to get your eyesight back. Once a cataract is detected, your vision will only continue to get worse. As soon as your ophthalmologist is able to refer you for cataract surgery, tell him you want to go ahead with surgery and get on the NHS waiting list.
From referral in early August 2015, I waited just over three months for my surgery date on 24 November 2015. Then, four and half months waiting for my second cataract surgery on 12 April 2016.
If you have any more questions, just ask. Happy to help.
Peace and Positivity,
high magical moon lovely to hear from you again just a few questions on your cateract operation
was yours afast growing cateract what time span did it grow in
soory about questions its just another hurdle to go through.Woke up still stiff in joints and my back but dont let it get me i get moving to get it loosend up.i bet yoga would be good.just hope it goes when tablets finish another 2yrs to go.
speak to you again magical moon
Lovely to hear from you again. Hope you are keeping well despite having to live with the ubiquitous side effects of Anastrozole. I'm still struggling with chronic pain and associated fatigue but haven't plucked up the courage to stop taking Anastrozole for a month to see if my pain reduces.
From the research I have done, I've not found a definitive answer about the chances of recurrence after 5 years of Anastrozole. The NHS Predict tool does give survival percentages at 5 years and 10 years taking and not taking hormone therapy but these percentages are estimates for general guidance and not case specific.
The possibility of a recurrence appears more dependent on the size, type and stage of an individual's original BC diagnosis. Although Anastrozole will help ladies who had a high ER+ score, it is only part of the bigger picture.
To be honest, I would love the medical research scientists to give us definitive statistics but nobody is going to be that bold. A BC diagnosis can be like a lottery and a recurrence can be too.
Sorry to hear you have developed a cataract. The cataract surgery on my left eye went very well last year in November. On 12 April, I will be having surgery to remove the cataract in my right eye. Please feel free to ask me any questions. I am more than happy to help you. I live in England and my eye surgery was done through NHS. My eye surgeon has a local private practice but is a consultant at my local NHS hospital as well.
Peace and Positivity,
Hi magical moon,
thought i would drop a line to ask how are you faring . Hope you are better with the anastrozole side effects, i have had a 2nd bone scan and have been put on Ad kal calcium tablets for bone thinning hope i don't have to take for life after finishing anastrozole(will ask doc)
does anybody know if there is much of a recurrence after 5 yrs of anastrozole?
gosh all these ladies describe many symptoms similar to my own mood swings ,being down ,forgetfulness etc its good to know other people have it too.
would like to ask you about cateracts operation as i have developed cateracts in my left eye.
do you live in england?
best wishes cils
Welcome to the thread.
It is always good to share each other's experiences so we do not feel alone or think we are imagining things. Just knowing someone else has had the same symptoms and can offer suggestions to ease the pain is beneficial.
I am sorry that you are having extreme pain in your wrists. It's no fun is it? Living with severe pain is a huge challenge especially when you are trying to get your life back to some kind of normality after BC. I do hope you find something that will ease your pain. If you do, be sure to come back and tell us.
Not long to go before your first anniversary. You always feel anxious at these milestones but it is lovely to get the confirmation NED.
Keep in touch and thanks for joining in.
I take Letrozole but get aches and pains etc and sometimes find a glass of tonic water very helpful, Also cod liver oil tablets do help too.
Somewhere on the boards some had good results with Devils Claw as well. All worth a try to ease the symptoms.
Like your friend, I am in constant pain. I'm on the Accord brand and have awful side effects. I tried the Teva brand and it made me feel even worse so I went back to Accord.
I know some ladies do find that side effects become less by changing brands.
Personally, I believe that my body cannot tolerate being deprived of oestrogen. Aromatase Inhibitors reduce the amount of oestrogen within the body by approx. 95%. My thoughts are that some ladies' bodies do not react as strongly to the reduced oestrogen so have minimal s/e's. Whereas those that have very bad s/e's are much more sensitive to the oestrogen deprivation. I am not a medical scientist so could be completely wrong.
Unfortunately, my BC was 8/8 ER+ so feel that my choice to stop taking Anastrozole is somewhat compromised.
Prior to being diagnosed with BC, I took HRT for 12 years. Absolutely no regrets because I felt absolutely FANTASTIC! I was topped up with oestrogen but stopped immediately on day of diagnosis. Now I am at the opposite end of the oestrogen scale with almost none. No wonder my body is reacting badly.
Well said. I am truly considering getting off of Anastrozole. I've been on it for 1yr 3 mos.
I have been on anastrozole for 1 yr 3 mos. I have never had knee pain or problems. I was running a half marathon each year. Since being on this drug, I have had 2 scope surgeries. (one on each knee). My knees ache all the time. My short term memory is really bad as well. There has to be a correlation!
Just read through the thread. I am also taking Anastrozole for BC. I have been taking it now for about 8 months after trying Letrozole. I feel like crap. My body is seizing up all over. The mornings are tough trying to move my hands, standing up very slowly, I hang on to every surface in the house as I move about, my ankles and knees are sore and stiff, lower back pain kicks in if I try and stand for too long. I have now started having pain in my leg muscles and random shooting pains down my legs and in my feet. I am so fed up and miserable, the GP has now put me on antidepressant pills too. Lost count of the medication I take ... Anastrozole, Naproxen, Omeprazole, Vitamin D, Glucosamine, Chondroitin, Gabapentin, Cocodamol, Trazodone .. Can't remember if I have missed anything out ! This has taken over my life, it rules everything. My husband and I are just living like flat mates now, he doesn't seem to get how things have affected me. Working full time is a struggle too, trying to focus on my job with all this is getting tougher and tougher. It frightens me also to think that the effects of this drug on my body are permanent, I thought things would improve once I was off it.
I started taking Anastrozole after finishing treatment of rads back in May 2015, at first all seemed ok apart from the odd ache here and there. Went away on holiday I the september, and walking up or down stairs started getting worse, saw my GP after my holiday and again the same thing was said to me its early days take your time? So I adhered to this advice come Noveber when I went for check up and see consultant to make sure all was ok, I mentioned this to him his reply come off the Anstrozole if you like? So I thought about this and then spoke to my GP again and the answer was the same come off the tablet for a month to see if its the tablet thats causing the aches and pains, so I did, absoloutley no change for me. I contacted GP again and said I would restart the tablet, I'm making an appointment toorrow to see GP again I feel that i have worsened and now reading all the comments it has made me feel that I'm not going mad! Ifeel that I'm now limited to what I can acheive during the day, I thought I would have been starting to get some normality back into my life after all the treatment and the op.I feel that my body doesnt want to do the things it used too, I walk my dogs out everyday with my husband and try and move about as much as I can, but by the end of the day I can just about shuffle about, I take codiene at night to relieve some of the pain, and getting up in the morning my body is so stiff it feels that if I mpve suddenly i'll snap. After having a bone density scan it said that I had some bone thinning going on, I can't believe that this tablet doesn't help with taht I know its a preventor and I'm worried it might come back, but I can't go on like this its debilitating, I'm only 57 but feel ore like an 80 year old my mum gets about better than me and she is in her 80's. It is also noy helping my depressive state of mind either. I try to be positive but some days its a chore.
Apologies for not replying sooner, I have not logged in to the Forum recently. Thanks for enquiring how I went on. It is kind of you.
I got my second year NED which was great news.
However, the decision to stop Anastrozole was left entirely my choice. I was offered the chance to switch to Exemestane but I declined. I told her that I was not happy to take Exemestane because the 'blocking mechanism' is irreversible. The thought of taking a drug that has irreversible effects does not appeal to me.
My chronic joint pain has continued but no one in the medical profession can confirm it is definitely caused by Anastrozole.
I was referred to a Rheumatologist in summer who carried out blood tests, ultrasound scans of my hands and a full body bone scan. The bone scan revealed no cancer (huge relief), ultrasound scan revealed osteoarthritis and blood tests confirmed my joint pain was not rheumatoid arthritis (phew!). She discharged me from her care.
The same as the breast cancer specialists, the rheumatology consultant could not confirm that my increased chronic joint pain was caused by Anastrozole. She could only suggest that I stopped taking Anastrozole for a month to see if my joint pain diminished.
At the moment, I am recovering from cataract surgery (another side effect of hormone therapy) so I have continued to take Anastrozole. I did not want too many changes to my body during recuperation.
In the New Year, I intend to stop Anastrozole for a month to see if my joint pain is reduced. I need to know one way or the other if Anastrozole is the culprit for ruining my quality of life.
Have you made any decisions about Anastrozole?
PS. When I got my second 'All Clear' result, I thought it would be easy to stop taking Anastrozole without hesitation. It seems I underestimated the power of my mind wanting to retain the 'comfort blanket' despite my chronic joint pain.