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Venlafaxine : the low down please?

14 REPLIES 14
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Re: Venlafaxine : the low down please?

Hello,

I see your post is more than a year ago, but I have good results with venlafaxine in regards to my hot flushes.  A couple time over the past couple of years, I've reduce the dosage but the hot flushes come back with a vengeance!!!

Here's info from online:

The 75 mg venlaflaxine dose resulted in a 60% reduction in hot flushes, while the 37.5 mg dose attended only a 40% reduction; however, the higher dose was responsible for greater side effects, including nausea, mouth dry- ness, constipation, and appetite suppression.

 

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Re: Venlafaxine : the low down please?

Hi all I was on sertraline for depression soon after diagnosis in September 2014. Didn't get on with tamoxifen or exemestane. Diagnosed with bone mets just before Christmas and have been on zoladex, letrazol and Ibrance.

Onc knows I had awful dripping sweats with the other drugs and gave his blessing for me to stop. When he suggested this new regime he offered venlaflaxine as one of its side effects is to reduce hot flushes. I was anxious about it because I've read all sorts of Scarry stuff on Dr Google, but so far so good. Nothing scary, moods pretty steady and flushes, although slowly increasing in frequency and intensity, are so far manageable.

We all react differently to these medications and whichever cocktail we're on. My thoughts are that we already have cancer so if there's something on offer to make it easier, grab it with both hands!

Ps I was 47 when diagnosed, er+ 8/8, 7x8cm tumour plus a 2cm one and spread to 26 lymph nodes.
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Re: Venlafaxine : the low down please?

I am on venlafaxine have been on it for depression for years
Will be strarting Anatrasole after Rads
I take 225mg a day for depression not for the breast cancer treatment/ side effects
However I do know that since my dose has increased I have such bad insomnia
Loss of appetite too.
But glad it is helping
I have been on it 10years and compared to other drugs it has less side effects and is tolerated better
Good luck x
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Re: Venlafaxine : the low down please?

Venlafaxine started working straight away for me. Some side effects for the first few days: nausea, headache and sore throat, but none if these since and I've been on it four about 4 months. The only thing is I now have insomnia ☹ I'm currently on 37.5 mg once per day and i take it in the morning (if I'm awake). I've heard that doubling the dose can help so I'm going to try over Easter weekend.
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Re: Venlafaxine : the low down please?

I'm still holding off the Venlafaxive - have them in the cupboard but very wary to take them. I took one back in August but after an hour I got a headache and felt very nauseated which lasted all night. I am quite aware that if these were side effects from the Venlafixine they would stabilise if I were to press on with it and continue regularly, but I felt to weird and spaced out the following day, and did not want to risk continuing it at that point as I had an interview.

Hows everyone else doing, mood wise, joint pain etc? 

 

J xxx

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Re: Venlafaxine : the low down please?

Hi

are you still on venlafaxine 

 

Just wondered how you've got on with them long term

 

Ive just been prescribed them

started on anaztrozole in .May then changed to letrozole. ( which seem the better of the two for pain)

I'm having terrible flushes and am constantly tired because they're waking me up a lot at night.

 

thanks

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Re: Venlafaxine : the low down please?

Well, on day three I have to say I'm pretty happy. Any flushes I have have been very minor and I've not had any horrid night sweats over the first two nights. Have to confess that I did feel a little ropey on Saturday, very tired and a bit spaced out but that seems to be clearing now. I find that the more active I've been the less tired I feel. I didn't imagine that it would have kicked in so quickly and I'm impressed. I definitely feel a lot more chilled out about other things as well.

 

Wish I'd done it months ago now.

 

Ruth x

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Re: Venlafaxine : the low down please?

Thanks Ruth, keep us posted!

The dose they are suggesting for me is 37.5mg. I am thinking I will give it a go as getting quite desperate for some relief, mainly from the sweats and tiredness and worrying.

 

J x

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Re: Venlafaxine : the low down please?

I took my first dose of this today - almost 14 months into taking Tamoxifen. The first few months I was fine but these last few have been terrible for flushes and night sweats. These past few weeks I've been having major flushes about every 20 minutes during the day and they have ramped up in intensity as well as frequency. So, went to see the Dr yesterday and she had no hesitation in prescribing this, Said it has a very good track record for this purpose. 

 

Too early to judge obviously but I have to say I've not had a significant flush since about an hour after I took my first dose - I'm on the slow release 75mg. I have felt rather tired today and slightly nauseous but hoping these side effects go away. Will report some more as things progress.

 

Ruth x

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Re: Venlafaxine : the low down please?

Thanks Sue C. My GP surgery is unable to provide any decent service at the moment, all but one are locums and the one permanent GP is someone I have never met. Can't get an appt very easily either but my oncologist has written to them to say they have recommended Venlafaxine and that I am thinking about it, can they prescribe it for me if I decide I wish to give it a go. I don't know what to do at the moment 😕 Jx

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Re: Venlafaxine : the low down please?

Hi Jo

Maybe worth visiting your gp.

I'm on letrozole so can't help you there. But also I take amitriptyline, which was originally given for tension headaches, but I think the oncologist would have prescribed them anyway, because they help with sleep and stress. Maybe worth asking?

Sending a hug x

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Re: Venlafaxine : the low down please?

Ok, well that's helpful - thanks Jo x

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Re: Venlafaxine : the low down please?

 
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Re: Venlafaxine : the low down please?

Hi J , I started taking Venlafaxine with Tamoxifen when I was diagnosed over two years ago and I feel great! Barely a side effect in sight , if I miss one then I feel awful so I know they work , give it a go! Xx Jo 

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Venlafaxine : the low down please?

Can I please hear from anyone, good or bad experiences? 

I am 18 months into hormone therapy, it's not getting any easier. My cancer was 8/8 oestrogen positive. I was 48 when diagnosed, I don't want recurrence and I am now pressing on with Zoladex and Examestane but it's been so hard, at the beginning I stopped everything for 8 months because I felt so bad I didn't really give any amount of hoots as to what happened - but I know this is the best current available treatment to prevent recurrence. I don't sleep, I feel crap, my joints hurt, I am hot all the time, regardless of whether I survive or not  I jjust completely resent the fact that I have had cancer. My oncologist and BCNs are suggesting I try Venlafaxine but I worry about trying it - am I being stupid? Thoughts anyone, please? 

 

J x