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Clinical trial or conventional chemo?

3 REPLIES 3
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Member

Re: Clinical trial or conventional chemo?

Hi Jo, just my thoughts having done 2 clinical trials at the Royal Marsden, one successful, one not.

Find out what phase the trial is at. Phase 1 is an escalating dose on a few patients at a time, looking mainly for drug tolerance. If you are right at the start the dose may be too small to be effective for you. Phases 2 and 3 are expansion ones where they have already ascertained effective doses.

Ask what success they have had so far in % terms. How many have dropped out due to progression or intolerable side effects.

Be aware of how much monitoring you will have as it can be fairly intense. 

In your shoes I would probably go for it once you have thrashed out the above. Wishing you the very best.

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Community Champion

Re: Clinical trial or conventional chemo?

Hi Jo,

I don't have TNBC but I have been reading up a lot on immunology and its advances for treating SBC.  It seems from the research papers/articles I have read that Immunology does seem to have positive effects on TNBC in particular and it looks like this is the way research is going forward in an effort to try and find the best way of treating TNBC.  I don't know if any immunology type therapies are routinely given on the NHS right now, so I think on the basis of both those things, my personal choice would be to give the clinical trial a go.  However its what you feel comfortable with, so maybe its worth having a more in-depth conversation with a medical professional about the clinical trial before you make your decision.

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Member

Re: Clinical trial or conventional chemo?

Hi Jo,

I'd go with the trial but that's just me.

There's lots of innovative treatments coming from trials.

Hope you hear from lots of other viewpoints. 

 

Angel Eyes 

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Member

Clinical trial or conventional chemo?

Dear All

 

I feel I’m at a crossroads unsure which road to take, I have been diagnosed with tnbc which has spread to the lungs, I have been offered a clinical trial a combo of immunotherapy and chemotherapy or just the standard NHS chemotherapy 

which way do I go any advice would be appreciated 

 

Jo