I have been on anastrozole for about a year. I had switched from tamoxifen because I was having such severe side effects. Up until the last two months I had been tolerating anastrozole with few side effects, but now I am having terrible joint pain. My hands, feet, and knees are swollen and I feel like I have severe arthritis. I have contacted my doctor and with his permission am stopping for two weeks. I'm one week in but there has been no change. I'm wondering if anyone can tell me how long to expect to wait for side effects to stop. I'm thinking two weeks won't be enough.