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Any suggestions for increasing my neutrophils after palbociclib?

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Re: Any suggestions for increasing my neutrophils after palbociclib?

Thanks for that information - who would have guessed that your tea was to blame? I hope you are well.

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Member

Re: Any suggestions for increasing my neutrophils after palbociclib?

 The defaul tea drunk in my house is Earl Grey, just because I take milk, but my husband takes it black. It's taken over a year for the penny to drop but the oil of bergamot which it contains comes from a shrub closely related to grapefruit and seville oranges. There's no problem with other citrus fruits, but (as with some other prescription medicines) the patient guidelines clearly warn you not to have grapefruit with it. As soon as I stopped drinking Earl Grey my monthly neutrophil count rose, and my red cell count, which had never dropped below the threshold also improved.

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Re: Any suggestions for increasing my neutrophils after palbociclib?

Sorry for the tardy response Janebell, but I don't come on here very often. I live in Cornwall, but I believe the Parsifal trial for palbociclib is international,  and is still open. "Subjects considered to be eligible comprises of postmenopausal women with ER positive and HER2 negative locally advanced or metastatic breast cancer that have not received any therapy for the metastatic disease". Hope this helps you find a suitable provider, if it is appropriate for you.

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Re: Any suggestions for increasing my neutrophils after palbociclib?

Hi just wondered where the trial is for palbociclib?and if they are still accepting patients ?

 

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Member

Re: Any suggestions for increasing my neutrophils after palbociclib?

Hi Lizzie

 

Please do give our Helpline a call, they will be able to answer any questions or concerns you have.

 

0808 800 6000

(text relay prefix: 18001)

We are open:

Monday-Friday, 9am-5pm
Late opening Monday and Wednesday 5pm-7pm,
Saturday, 9am-1pm

- See more at: https://www.breastcancercare.org.uk/information-support/support-you/someone-talk/call-our-helpline#s...

 

Best wishes
Anna
Digital Community Officer

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Any suggestions for increasing my neutrophils after palbociclib?

So bone mets was not exactly great news, but I was accepted on to the trial for Palbociclib with Letrazole, and completed the first cycle OK - or so I thought until the routine blood tests showed really low neutrophils (.86 with a threshold of 1.0). Never mind, they said, continue with the Letrazole, have the denosumab which is also due, and we can give you Palbociclib next week when your blood count has improved. Unfortunately, it went down instead of up (.81), so they're leaving me another week...hence my question: Does anyone have any ideas for increasing my white cell count by next Friday? The associated question is that although Palbociclib has a reputation for neutropenia, (probably why they only give it for 3 weeks out of every 4), does anyone know of a similar effect from denosumab/xgeva? I'm curious because this would explain why the count was lower 2 weeks after the last tablet of P than it was 1 week after it.