Hi Jeannie, yes I've been on a trial for 20 months now so I'll try to help. I could rabbit on for hours but in a nutshell...I haven't heard of your trial but the questions I'd ask are:- is it a dose escalation phase...when small groups of patients are given escalating doses, measuring response and side effects. If so, what level are they at now ( sometimes the dose at the start can be too low to be effective) If it is at a dose expansion phase is there a placebo group? How often are scans done? I wouldn't want to be in a placebo group for long, unfortunately you don't know...except by maybe having side effects if you are in the drug group.
Id also ask what the criteria are for going on the trial...sometimes quite stringent and what they are for the trial to be deemed unsuccessful for you. You are allowed to leave any time you want, by the way!
i have been very well monitored throughout my trial and it has been very successful. If I get a 20% increase in my monitored tumour size then the team would take a view as to carrying on.So far I've had slow but consistent decreases. I get checked over at least once a fortnight, I'd also look at number of hospital visits and impact on your life. Sorry, must run! Ask any more questions x
I’ve been on capecitabine for the past 2 1/2 years for liver & bone mets & has been stable until last week. I’ve just found out that I now have further lesions in liver & possibly skull (I’m waiting on head ct to confirm that). My oncologist was going to change treatment to faslodex, but on talking he mentioned I might be eligible for some clinical trials that are ongoing just now. I’ve received info about a trial using Faslodex + experimental drug GSK525762 but it’s only a phase 1-2, so very early experimental stages. It also lists a whole load of side effects which are very daunting. I don’t know what to do. I’m going on Thursday to speak to them & I’ve got apt with my own oncologist today as well. I’m just looking for as much info as possible before I make my decision. I’m otherwise healthy & lead an active life. I want something that is going to help me not make me ill. I don’t know what to do!!!!!!!