Hello ladies. I completed my chemotherapy (FEC-T with targeted therapy) at the end of 2016 and I can confirm that drinking 2 litres of fluid daily does seem to help reduce the effects, even though it sends you to the loo a lot (with FEC particularly). On the only occasion I managed to drink 1 litre before FEC chemotherapy (second infusion), the SEs were significantly reduced and I didn't get nausea at all. How much that was down to the extra drinking (plus salty soup) before the treatment, and how much it was down to a different anti-sickness drug I cannot say, but certainly the two in combination helped (I had the same anti-sickness drug the third time and it didn't work!). However, I should add a note of caution, because drinking too much can give you hyponatremia (sodium deficiency), especially if you drink a lot after having chemotherapy but are unable to eat much or anything at all, because of nausea. This happened to me following my first and third FEC infusions, and both times I ended up in A&E as a result. The first time it developed into cerebral oedema (swelling on the brain) before anyone realised how serious it was, and I was in hospital for 5 days being treated for this. One of the anti-coagulant sickness drugs I was given (Domperidone) could also have contributed and made it worse than it would otherwise have been. The second episode (following the third infusion) it was less serious, and didn't develop into oedema, because I realised what was happening and got to A&E quicker, so they got it under control quickly and I only had to stay in overnight. Just so that you know, the main symptoms of hyponatremia are confusion, difficulty communicating, uncontrollable shaking and blurred/ double vision. If you start to feel any of these effects, tell those with you, because the quicker you get to hospital the better. I hope this never happens to you, and I don't want to worry you because these effects are rare, but I thought I should warn you. Take care and hope you are all feeling better soon. The excessive wee-ing should go away once you are off FEC but if you are going on to T afterwards it has side effects of its own. You'll probably still be spending a long time on the loo but for other reasons...