Bumping up for Dear Life
I am not experienced enough to talk about this drug but there are ladies on here who are. But good luck and keep posting to let us know how you get on with this treatment.
Hi Mary, think you've picked up an old thread but I'm interested in the fact you've been on Ibrance for 11 months. Are you from US? I'm starting a drug trial with Ibrance and another drug so I'd like to pick your brains in a few weeks!
Hi, i am in my 11th month of Ibrance. All bone and lymp mets are gone. tumor is shrinking. Fatigue is unbelievaeble. and i work hard to keep my numbers up. Also started Xgera, for the bone cancer. Questiions...please. i dont know what you need to know.
L:adies, thaks for the info on this...i to am er+, her2- with skin mets which dont seem to be responding to any hormone therapies or even chemo at the moment...on eribulin currently. Would be especially good if this could be used with faslodex as that seems to be the only option left for me...so depressing when nothing seems to work isnt it, especially when there are drugs out there which could help. x
Thanks for reply.
I did speak to onc but she turned her nose up and brushed my question aside. It's frustrating really as if this Ibrance works and prolongs life then shouldn't our oncologists talk about it and maybe look into it if they haven't come across it before?
Would love to know if anyone out there is on it and or it's here in UK?
I think there is a paloma trial at the Marsden. If it is the same drug ( and I think it is). The oncologist in charge delivered a paper last month about it. He was very positive about the results to date.
As Mermaid said, there are a number of women in the States on this drug. It's marketed by Pfizer and is paired with Femara (letrozole), although I believe some oncologists are starting to use it with Faslodex (fulvestrant). It may potentially be paired with other drugs, so there is some interest about that. The US website mentioned by Mermaid does have an active thread under Stage 4/metastatic cancer.
I believe this drug is currently expected to be rolled out in the UK during the latter half of 2016 although I don't have any knowledge of costs to the NHS and how that process works.
I find it very frustrating that any oncologist wouldn't keep up to date with possibly helpful drugs - maybe your onc doesn't want to raise any hopes as it's not actually approved in the UK yet?
Whilst you wait for the other users to reply may I suggest you give the BCC helpline a call on 0808 800 6000. Here you can talk through your thoughts and questions and the staff there may have further information on this new type of treatment.
Lines are open weekdays 9 to 5pm and Saturday 10 to 2pm.
Best wishes Sam, BCC Facilitator
this is for anyone in the know and wondered if any light can be shed on this new drug? It's for secondary breast cancer which is hormone positive and her2 neg. It's taken alongside Letrozole or another hormonal drug.
this is an extract i gleaned from Inspire website:
* Palbociclib – a type of biological therapy that inhibits cyclin-dependent kinase (CDK) 4 and 6. Approved by the FDA in the US for breast cancer (it was given accelerated approval due to its “breakthrough status”) and is used for the treatment of ER-positive and HER2-negative breast cancer.
If anyone does know anything about Ibrance (palbociclib) then I'd like to discuss further.