I have been on Kadcyla for a year and it seems to have worked very well for me so far. Keeping things stable and on the whole minimal side effects - certainly nothing like side effects from the taxanes and Fec which for me were truly awful. I have managed to maintain a pretty good quality of life. Have the odd 'off day' once or twice each cycle which may or may not be treatment related.
Hope that helps and am happy to answere any more sepcific questions you might have.
Welcome to the forum - a great source of information and support.
There is another, more up to date thread on here about Kadcyla (this one is quite old). I will 'bump' it up the page so you can read it as there are ladies on there who are currently having this treatment.
Sorry I can't help any more.
I am Nancy, I live in Belgium.
Here on the internet i cannot find much info about Kadcyla.
So i hope i can find some answers here....
My story: my breastcancer has spread to my bones, I already had FEC and 2 times Taxotere.
After that i have had herceptin. Nothing works, not even the chemo, because the tumor i was treated for is also back. Now my last hope according to my doctor is Kadcyla.
Even with this, she gives me a survival rate of 5% for the next 5 years.
After all this time i am a bit sceptic, why should this work then?
My doubt is big, to give this a try, first i want to know more about the SE and if my life will be comfortable to live, if you know what i mean.
So what my question really is: are the SE worth it?
Thanks in advance for your help.
Great timing on secondary BC day! Scotlands medicines consortium has declined to approve funding for Kadcyla because of concerns re cost effectiveness.....according to BBC news scotland
Nicky is right - its Capecitabine and Lapatinib that crosses the blood brain barrier. BUT have read a couple of interesting articles on people who have had cyberknife or surgery which has opened it up to let Herceptin across? Unfortunately I can't have surgery but if I can in the future then hopefully this might be another option for us?
Correction!!!! In England the money comes out of the Cancer drugs fund. In Wales its largely unavailable xcept on trials...I am not sure of the situation in scotland or NI.......Please keep remembering those in the UK who end up going without treatments or paying for them themselves despite contributing equally to the funding.
I am starting Kadycla this week for secondaries in bones and lungs. Here in the uk the money comes out of the cancer drug fund which is money allocated to fund treatments like this.
I did, mainly because I thought I was starting a cold, as its taken a few sessions to see the pattern. You have to be careful about paracetamol hiding a temperature, so be careful in case it is an infection and not a side effect.
new to this thread, I've had 7 cycles of Kadcyla and have had flu/cold symptoms after last 3 cycles for 2 or 3 days. Also tired for 3 days afterwards but otherwise feeling remarkably good and with shrinkage reported after my scan. It would not be as easy to keep working full time like I did on Herceptin, but for me its a truly remarkable drug and every active and otherwise healthy person who is HER+ and gets progression while on Herceptin should be able to have it - a longer life and a good quality of life while on it has to be worth the money, after all we won't be drawing our pensions etc. so we aren't going to cost the government any more money than most people.
i had the sickness nearly every morning after the 1st 2 cycles
and theres no chance im pregnant lol
however this cycle i havent had the sickness feeling thankfully.
good luck with it xx
That is impressive and I am so pleased for you - great news. May it continue working for you and giving you a good QOL. Thak you for your reassurance and taking the time to let me know. xx
i have had 4 cycles of kadcyla, and today i went to see my oncolgist to get the results
of my 1st CT scan since starting kadcyla,
Its good news
I have mets in my spine,shoulder,foot & recently multiple mets in my liver,
the CT shows that kadcyla has cleared up my liver,no sign of cancer now
my bones are stable too.
my oncologist has said he is pleased with the results so far and i can continue on it,
my 5th cycle is due next tuesday.
i am so relieved to hear its working, i have felt so stressed waiting for this result.
I hardly get any side effects,
i keep my hair, it is thinner but i have also started tamoxifen so it could be that
slightly achy bones 1st few days after my treatment,
and i have noticed i am more tired.
saying that i still go to work & the gym so its very doable
Thanks for reply Sue. yes unfortunately Herceptin does't seem to be holding things as well - at least according to my scan results. Disappointing as it suited me so well. Were you previously taking Herceptin?
It would be good to hear how you get on. I have not decided for sure yet but there don't seem to be many other options right now.
Hi there, I can only comment on kadcyla from a friend's perspective, not been on it myself. My friend started on it in April or May, i think. She has not lost her hair and I think she's been generally quite well on it except for some peripheral neuropathy where she has lost some feeling in her fingers.
She has not had a scan yet since starting it, so I don't know how it's affected the cancer.
Can anyone give me any feedback as to how they have found taking this Kadcyla. . It has been suggested that it would be good for me.Have been taking Herceptin for the past 18mths and tolerated this really well so it is a difficult decision to make.