68.4K members
1.2M posts
cancel
Showing results for 
Search instead for 
Did you mean: 

Letrozole and grapefruit

6 REPLIES 6
nicky08
Community Champion

Re: Letrozole and grapefruit

Hi

Although this is an old thread, and 2catlady is sadly no longer with us, it is definitely relevant.  In fact grapefruit interferes with the absorption of a lot of medications so the advice is not to have it if you're on other meds such as blood pressure tablets, blood thinners etc.  As bon has said other fruits should also be avoided - best check with your GP or oncologist.

Nicky x

bonariensis
Member

Re: Letrozole and grapefruit

Hi Bclady

I'm not on letrozole, I'm on exemestane, but I don't eat any colour of grapefruit, it's a no no when taking any aromatase inhibitor which both letrozole and exemestane are. Grapefruit interferes with your absorbtion of the drug in your gut. I also don't eat seville orange marmalade which is a shame because I used to make and eat bucket loads. I don't think you should eat pomegranates or starfruit ether. Smiley Sad

Bon xx

Bclady2017
Member

Re: Letrozole and grapefruit

I have a question is ruby red grapefruit ok to eat while on Letrozole . They don't eat grapefruit but didn't specify which one as I really don't like the white. But I do however eat lots of oranges 1 every night. In October I also eat pomegranate.
2catlady
Member

Re: Letrozole and grapefruit

Hi,mrs blue & ponsmuir ,thank you for your help,I'll ask on Monday when I see my onc.I'm glad other citrus are okay as I eat loads of oranges and their juice.
Good luck with your scan mrs blue xxx
Huge hugs to you both,Helen xxxx
ponsmuir
Member

Re: Letrozole and grapefruit

Helen,
I've read this too but no one has mentioned it to me. I am not a fan of grapefruit so it's not a problem. I love satsumas though!
I should imagine that as the specialist who wrote that on the Macmillan site is so specific. it just applies to grapefruit. Ask your Onc if you are worried. Or maybe a pharmacist.
mrsblue
Member

Re: Letrozole and grapefruit

Hi Helen, interesting q as I was just wondering the same... I'm on letrozole for the 2nd time having had 4 different chemos and several other treatments at various times.

As always, the mantra is, "ask your onc / BCN" but I hope it may be helpful to make some general comments (I worked on a food-science database before I retired).

There is a compound found in grapefruit, also in smaller amounts in Seville oranges (the bitter oranges used for making marmalade) which can interfere with the body's ability to process many drugs.  This compound is NOT found in other types of orange / citrus, and I don't think it occurs in lemons or limes either.  Citrus fruits in general have health benefits.

Hope this helps... and that you do well on letrozole.  I tolerate it well, though I do have "letrozole-legs" - that heavy feeling on getting out of bed.  A scan and blood tests are booked for later this month - see whether letrozole is still working for me.

2catlady
Member

Letrozole and grapefruit

Hi,lovely ladies ,just a quick question,I've just been reading about letrozole on the Macmillan website and it says avoid grapefruit and grapefruit juice! My onc never mentioned this to me or anything I should avoid . Has anyone heard of this? Are all citrus fruits to be avoided ?
Hugs to you all,Helen xx