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REACT Trial - anyone had a bad reaction to it?

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Re: REACT Trial - anyone had a bad reaction to it?

I'm on the REACT trial, and have not had any adverse reactions, but then I could be on the placebo...

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Re: REACT Trial - anyone had a bad reaction to it?

Yes. I had a terrible reaction to it. Wouldn't recommend celecoxib to anyone.

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Re: REACT Trial - anyone had a bad reaction to it?

Hi

Here is some info on the REACT Trial:

A trial looking at celecoxib for women with breast cancer (REACT)
This trial is looking to see if taking a Cox-2 inhibitor called celecoxib, after treatment helps to stop early breast cancer coming back in women.

Many breast cancers respond very well to treatment. But this is not always the case and sometimes breast cancer can come back. Doctors think that celecoxib might lower the risk of some cancers coming back. Celecoxib is a type of drug called a Cox 2 inhibitor. These are a type of anti inflammatory drug. They block a protein, called Cox 2, that may help cancers to grow.

The aim of this trial is to compare celecoxib to a dummy tablet (placebo) for women with early breast cancer. The doctors want to find out whether celecoxib helps to stop breast cancer from coming back. And to find out more about the side effects of celecoxib

As with trials you never know if you are on the placebo, or on the drug or if the drug will work. There is no harm in asking your Breast Care Nurse about it. It is not a new drug it is currently being used for arthritis. I amso disappointed that I reacted to it, I will give it another go once I have finished radiotherapy.

Good luck

Re: REACT Trial - anyone had a bad reaction to it?

Hi.
Sorry to hear you had a bad reaction, I had a bad one to Taxotare, so know a bit how you feel, was horrid.

sorry I cant be of any assistance with your question, but I am interested in your comments about this trial 'to try and stop the cancer from returning'. I wondered if you would tell me a bit about it, ie, who is eligable for it, how does it work, is it an alternative to something like Herceptin? Im only 36 and with two young children to consider I am interested in anything which could prolong my life. Sorry for turning your own thread around on you, hope you dont mind all of my questions.

Thanks Ness1. x

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REACT Trial - anyone had a bad reaction to it?

HI

Is anyone out there on this trial of Celecoxib for stopping cancer returning?

I was on it for 10 days and then came out in an horrific allergic reaction all over my body. It was like a red birth bark from head to toe, and it also made me feel a little unwell. I have had to come off it for now until at least I have finished my radiotherapy

Anyone else on this trial?

Thanks

CrystalT