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St John's Wort and Anastrozole

Community Champion

Re: St John's Wort and Anastrozole

Hi Cherry it's a bit of a minefield isn't it.Post this query in the ask the nurses section and hopefully you will get to informed advice ..Hope you feel better soon.Jill.

St John's Wort and Anastrozole

Hi All,


I've been having a bit of a stressful time of late and have ended up with some low depression and anxiety. It crossed my mind I could try taking St John's wort temporarily until I feel happy again so, as I take anastrozole,  I googled for any interactions. Most comments and advisories sounded ok but one said : "Aromatase is an enzyme closely related to P450 and several herbs interact with P450 - St John's wort the most prominent. People should avoid herbs known to interact with the P450 system."


Of course, I don't know what I'm saying! But can anyone else enlighten me or suggest a natural pick up from feeling low?  Many thanks, love Cherry