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Which anti depressants suit you being on tamoxifen?

31 REPLIES 31
miscally
Member

Re: Which anti depressants suit you being on tamoxifen?

Thank you Isabelle. I took the first one this morning, so we will see how it goes. Fingers crossed.
Take care and best wishes.

izzypal
Member

Re: Which anti depressants suit you being on tamoxifen?

Hi Misscally,
I've been on Citalopram 20mg of 4 months now and I don't know what I would have done without them. I really didn't want to go on them at first but everything was getting on top of me and I said I would give them a try and they have been very good. I have also been on Arimidex for 5 month now and the Citalopram helped to lessen the se's of the Arimidex, which were getting rather painful within the first week or so of taking them, sore feet and legs and night sweats ect, they have all subsided for now anyway.
I hope you find them as helpful as I have.

Best Wishes,

Isabelle xxx

Gwendolyn
Member

Re: Which anti depressants suit you being on tamoxifen?

What a useful thread as I have just been prescribed citalopram and was also panicking after reading the leaflet which is terrifying.I checked with my BCN and she looked citalopram up in a book that they have and it's ok to take with tamoxifen. I had hoped to take St Johns Wort but she said no. Still worrying but think I need to try it.

miscally
Member

Re: Which anti depressants suit you being on tamoxifen?

Hi Viv,

Thank you. I just read the leaflet with the tablets and panicked badly!
I will give them a go tomorrow.
Thank you again and best wishes.

vivrog
Member

Re: Which anti depressants suit you being on tamoxifen?

Hi Miscally

I have been on Citalopram (40mg) now for 4 years and have had no SE s at all. I am also now on Tamoxifen and no interference there.

Viv x

miscally
Member

Re: Which anti depressants suit you being on tamoxifen?

Hi Caroline,

Thank you, mine are 20mg, but I will give them a go!
Thanks again.

carolihne
Member

Re: Which anti depressants suit you being on tamoxifen?

Hi,
I have been taking citalopram for nearly a year now. I take 10 mg a day which is apparently a very low dose. They have really helped me cope-no more panic attacks, no dreadful mood swings and I just feel 'normal'(whatever that is). I would recommend giving them a try they have made my life (and my families) so much better.
good luck
Caroline

miscally
Member

Re: Which anti depressants suit you being on tamoxifen?

Hi all,

I have just been prescribed citalopram for depression and am very scared. How had is it? It says that driving may be affected, has anyone experienced this? My GP said I did the right thing going to see him but now I'm not so sure. It is all too much at the moment. I feel really pathetic, no chemo and almost finished rads, but I have not had any time off and have tried so hard to keep going, I think I've burnt out!
Sorry, just scared of going down this route.

Lulu34
Member

Re: Which anti depressants suit you being on tamoxifen?

emelf sertraline is the one i was on.... 50mg and then went up to 100mg when i found out i had the brca 2 gene then reduced back to 50mg before stopping it.

however i just stopped it suddenly and apparently you are supposed to reduce it ie every other day then every 3 or 4 days before stopping it completely so i developed some very unnerving side effects... actually thought i had brain mets because of it... was spacing me out and my brain was having funny turns.

all ok now but i know if i ever go in ADs again to reduce them gradually.

Lxx

Guest
Not applicable

Re: Which anti depressants suit you being on tamoxifen?

Thank you Jo.Well I did have all the faith and trust in the world for my(professor) Oncologist,not any more.

Mel xx

Emelf
Member

Re: Which anti depressants suit you being on tamoxifen?

Saw my doc yesterday. He said St Johns wort was a no no.
Hes put me on Sertraline. NOt heard of it. He said it was an SNRI but looked it up and it says its a SSRI. So confused!!

Anyway, cant start them yet as might be pregnant. Find out tomorrow. Come of tamoxifen just in case. Very nervous!!!

Jo_BCC
Member

Re: Which anti depressants suit you being on tamoxifen?

Hi Melly2

There is some evidence to suggest that due to changes in liver metabolism caused by St John’s Wort, levels of tamoxifen may be lowered. This in turn may result in tamoxifen being less effective.

We would always encourage anyone to seek advice from their medical team and a qualified herbalist before taking any herbal preparations. A specialist hospital pharmacist may also be able to help. To find a qualified medical herbalist, please see useful organizations at the back of Breast Cancer Care’s Complementary therapies booklet. http://www.breastcancercare.org.uk/uplo ... ug07_0.pdf

Kind regards

Clinical team

lupin15
Member

Re: Which anti depressants suit you being on tamoxifen?

Hi
I took St Johns when i was on tamoxifen but was told i should not take it when i change to aromasin. It would be good to get more information so people can make the choice. I am lucky that i do not need to be on anything at the moment but would hate the thought that i had not choice.Have any test/tresaerch been done on this ?

Jo_BCC
Member

Re: Which anti depressants suit you being on tamoxifen?

Hi Melly2

I will pass this on to the nurses here regarding St. John's Wort and see if they have any comment to make regarding this.

Take care,
Jo, Facilitator

Jeannie
Member

Re: Which anti depressants suit you being on tamoxifen?

Dear Melly2

I wish I could remember who told me not to take St Johns Wort. I have a feeling it was Bristol Cancer Care (now Penny Brohn Centre) but cannot say for sure. Perhaps if your cancer is not ER+ and PR+ then you can take it. Mine is 100% ER+ and 100% PR+ so I would not be inclined to go down that road. If in doubt, I would leave out.

Wishing you well.

Jeannie

Guest
Not applicable

Re: Which anti depressants suit you being on tamoxifen?

I thought I would have a quick look on internet and see if I could find these studies but the only information I could find say's it's NOT safe to take St John Wort whilst on tamoxifen.So is my Oncologist wrong, is it just his opinion,should I not take it.We put our lives in there hands don't we.

Mel xx

Guest
Not applicable

Re: Which anti depressants suit you being on tamoxifen?

Hi my Oncologist a Professor at the Marsden in Sutton was not happy with me taking any antidepressants and advised me to take St Johns Wort,he said there had been studies done and it was perfectly safe.

Bet wishes Mel xx

Emelf
Member

Re: Which anti depressants suit you being on tamoxifen?

Cant take st johns wort with tamoxifen apparently. Shame as would rather take herbal.

Im confused wuth the 2 groups of anti depressants.

I did try citalopram last year. I took one n I hated it I didnt bother carrying on. It was like taking a bad ectasty pill and i really didnt want to feel like that so it put me off n ive been scared to take any ever since!

broomsticklady
Member

Re: Which anti depressants suit you being on tamoxifen?

I've certainly found for my depression and anxiety that duloxetine works for me - tho as I say I'm on Arimidex not tamoxifen now. I've had no really bad side effects from it, and am taking 90mg which is 50% more than the recommended max dose, so think I'd be suffering big time with side effects.

The 'problem' with them I suspect is the psychiatrists who prescribe them - a new one for me wanted to put me back onto something else - can't remember what but it pre dated SSRIs and SNRIs, and I wasn't prepared to play ball with him and change - when questioned, he'd never used SNRIs before so was dubious abou them. The psychiatrist who put me on it was fairly young and forward looking - she also got me onto cognitive Analytical therapy, which has helped me a lot, whereas the old CBT just washed over me - it didn't tell me why I am as I am, which the CAT has.

Good luck!

Nina

lupin15
Member

Re: Which anti depressants suit you being on tamoxifen?

How about St Johns Wort...not sure about the spelling ladies. I took that for a while and it is herbal. You cannot take it with all meds so check with your doctor.

Jeannie
Member

Re: Which anti depressants suit you being on tamoxifen?

Dear Broomsticklady

I've just checked the details within my Venlafaxine packet. You are correct in your understanding, Venlafaxine is a SNRI. I'm left wondering if it would be better to take a SNRI drug in light of the uncertainty as to whether SSRI drugs affect the work of tamoxifen.

Would be good to have your thoughts.

Keep well.

Jeannie

judyw47
Member

Re: Which anti depressants suit you being on tamoxifen?

Another citalopram user here which is working extremely well for me with tamoxifen. Good luck and best wishes to you all.

Judy x

Emelf
Member

Re: Which anti depressants suit you being on tamoxifen?

Thanks for all your comments. Its really helped. Seeing my GP on Wed.

daisyleaf
Member

Re: Which anti depressants suit you being on tamoxifen?

Hi
I was on seroxat when I went on to tamox, but had to change to citalopram, which is apparently fine, and works well for me.
good luck
monica x

Lulu34
Member

Re: Which anti depressants suit you being on tamoxifen?

i was on sertraline which worked fine with tamoxifen... stopped it about 2 months ago and had some naff SEs cos i stopped it too quick but otherwise it was fine.

Lx

broomsticklady
Member

Re: Which anti depressants suit you being on tamoxifen?

Venlafaxine is not an SSRI in my understanding but a SNRI, which has an effect on the neo adrenaline as well. I take another SNRI now, duloxetine, which works reasonably well for me, having 'beaten' prozac - even on max dose I was still curling up howling in bed under the quilt with ear plugs in, just shutting myself away from the outside world. SNRIs seem to be less used than SSRI's and often seem to be teh preserve of psychiatrists to prescribe initially rather than GPs.

janey123
Member

Re: Which anti depressants suit you being on tamoxifen?

Hi, I'm also on venlafaxine, only started it a couple of weeks ago as wasn't coping well, still early days and on a low dose (37.5mg). Am seeing my gp for a review next week so dont know if she'll change the dose, hasnt made much differnce to the hot flushes as yet unfortunately....hope it will in time. Started tamoxifen about a month ago,
Good luck xx

Jeannie
Member

Re: Which anti depressants suit you being on tamoxifen?

Dear Emily

I go along with gocat on this one. My cancer was over 3 years misdiagnosed so you could say I was rock bottom when it was discovered I had breast cancer and had watched it grow throughout that time. I've had a fair amount of anti depressants because of this. At first I had diazipam, then prozac. However, when I told my oncologist what I was taking he suggested I went on Efexor Venlafaxine - he said it would also be helpful with my hot flushes. I then moved house to an new area and my GP suggested Cipralex which I took for about six months. I then read that Cipralex belongs to a group of anti depressants called selective serotonin reuptake inhibitors (SSRIs) and could interfere with tamoxifen. I came off them. I know that Efexor Venlafaxine is also a SSRI but my understanding is that if you have to take one, this would be the best one to take. I still have post traumatic stress treatment and my therapist suggested MorEPA (basically fish oil) and I really do think it helps. I hope I haven't confused you and you find my posting helpful.

Let me know how you get on.

Jeannie

broomsticklady
Member

Re: Which anti depressants suit you being on tamoxifen?

I'm not taking tamoxifen for my cancer, but did participate in the IBIS 1 trial from 2000 - 05, and I discovered on diagnosis, having been advised to have my IBIS code broken, that I was on tamoxifen. Must admit I had no idea - no side effects whatsoever despite being pre menopausal at the time!!

Throughout my IBIS trial I took prozac / fluoxtetine at varying doses from 20mg pd to 60 mg. IBIS knew about this as I declared it, but never queried the parallel use - presumably had there likely been any effect they'd have not wanted me on the trial as I might skew results. But its occurred to me since starting to type - this may be newer research so I've probably not helped much!!

gocat
Member

Re: Which anti depressants suit you being on tamoxifen?

I was on prozac when diagnosed with bc. When put on tamoxifen I had read on here that prozac prevents tamoxifen working properly and saw advise to change to effexor. So GP put me on effexor 75mg daily. Now decreased to 37.5mg daily. Suppose to help with the hot flushes too which is hard to tell as not been off the effexor so cant compare.

cass141
Member

Re: Which anti depressants suit you being on tamoxifen?

Bump

Emelf
Member

Which anti depressants suit you being on tamoxifen?

I wanted to know if ther were certain types of anti depressants that work well with tamoxifen?

Is anyone on them and got on well with them?