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Hi Naz


Thanks for posting.


It sounds as though you are having a difficult time with menopausal symptoms so it’s understandable that you want to know what the evidence is related to the use of HRT for women who’ve  had breast cancer.


Currently there is no evidence that HRT, is safe for women who have been treated for breast cancer.


Evidence from two randomised trials  concluded that women who took HRT after they had been treated for breast cancer were at increased risk of a new breast cancer event. One of the trials was terminated early because the trial indicated an unacceptable risk to the women who were taking HRT.  Extended follow up from these studies confirmed the original findings. 


As you rightly point out menopausal symptoms can impact quality of life and it is possible to get a recurrence without HRT.  This is why some specialists will consider prescribing low dose hormone treatments for a short time for vaginal dryness. These include oestrogen pessaries, tablets, cream or a ring that are applied directly to the vagina. Vaginal oestrogen may be more safely prescribed for women taking tamoxifen as tamoxifen is thought to counteract any oestrogen entering the bloodstream.


You may also be interested to read what the American College of Obstetricians and Gynaecologists (ACOG) say about this.


Do call our free, confidential Helpline if you would like to talk this through or have any further questions. The number is 0808 800 6000.


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Best wishes




Breast Cancer Care Nurse


Please read the Ask Our Nurses disclaimer. This thread will now be closed from further replies. If you have any additional questions or would like to provide feedback, please start a new thread.





Thanks for posting your question.


We hope to be able to respond to you tomorrow.


In the meantime our Helpline is open from 9am tomorrow if you would like to talk things through. 


If you do phone our Helpline please let us know that you have asked a question on our forum so that we know your query has been answered. Thank you


With best wishes.




Ask Our Nurses Co-ordinator

Please read the Ask Our Nurses disclaimer .





I am experiencing many frustrating menopausal symtoms. My BC diagnosis was 10 years ago and in that time, I have been cancer free. I recently visited my GP to discuss HRT. They wrote to an oncologist who advised against it, even vagifem!

Where is the evidence to suggest that taking even a low dose of HRT, causes a recurrance? Where is the evidence that vagifem causes a recurrance?


I am having to pay to see a private specialist (borrowing the funds) to try and obtain HRT that way.


Frankly, I am dismayed. What about quality of life? I may get a recurrance even without HRT. Do they have a crystal ball??