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Re: Tamoxifen/Menopace

Hello Edmunds

Thank you for posting your question.

Many people ask about vitamin and herb supplements as they want to do as much as possible to be healthy. There is often the belief that vitamins and herbs are safe as they are considered natural.  However, herbal treatments don’t have to comply with the same regulations or rigorous testing that conventional medicines do. There is much we don’t know about supplements and herbal remedies.  For many products there is a lack of research to support their use, and some can interfere with conventional medicines including cancer treatments. 

You can search this American website here for information about the individual herbs and vitamins in the Menopace supplement. Each has sections on existing evidence and what known interaction there is with other medications.

You may find it helpful to speak to your breast care nurse, hospital doctor, your GP, or a pharmacist about taking Menopace and they will be able to advise on any interactions with tamoxifen.

The ingredients for Menopace do list several ingredients, such as Vitamin A, Vitamin E and Soya isolvlavone which people who have had breast cancer are usually recommended to avoid.

For example, NICE  guidelines state- ‘Do not offer soy (isoflavone), red clover, black cohosh, vitamin E or magnetic devices to treat menopausal symptoms in women with breast cancer.’ [2009]

Our Complementary therapies, relaxation and wellbeing booklet (p18) contains further information about herbal treatments. 

Menopausal symptoms are a very common side effect of tamoxifen. If you are experiencing these side effects, you can speak to your treatment team or breast care nurse. They may be able to refer you to a menopause clinic for advice or suggest some self-help measures to manage any symptoms you have.

Do call our Helpline if you would like to talk this through or have any further questions. Your call will be confidential, and the number is free from UK landlines and all mobile networks. The number is 0808 800 6000, (Relay UK -prefix 18001).

If you would like a nurse to call you do complete this form. Ticking the box agreeing to a call back.

Our opening hours are Monday to Friday 9am - 4pm and 9am -1pm on Saturday. Out of hours you can leave a message and we will call you back when we next open.

Best wishes


Breast Care Nurse

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Hi. i had lumpectomy/radiotherapy only and now on tamoxifen(since March).  ER+ HER negative. i have been also taking Menopace supplements(standard one) but not sure whether i should be-concerned that this may conflict with the tamoxifen?? Can you advise please