Thanks for posting. It sounds as if you’re facing some difficult decisions about your endocrine therapy.
It’s not possible for us to make recommendations for an individuals’ situation.
However, based on the criteria for the Allred scoring system, the percentage of positive oestrogen receptors indicates that a score of 3 out of 8 is positive.
As Yolande55 suggests, many women take tamoxifen with few problems of side effects.
You don’t say what age you are, or your menopausal status, which may affect your decision making.
It would be a good idea to contact your specialist team again to discuss your concerns. The oncologist could add your details into an online tool, such as Predict, to give you a result of the benefit you’d gain from the options offered to you.
We offer a range of free supportive services that you might be interested in. For more details about all of these services, please see the information on the link.
Our services normally includes face to face support at a number of locations throughout the country. However, due to the COVID-19 pandemic, we’ve had to take the difficult decision to suspend all of our face-to-face services for now.
Outside the current coronavirus situation, our Moving Forward courses also provide information, support and professional guidance on how to cope with, and adjust to, life after breast cancer treatment. We are offering an online Moving Forward service when treatment has completed.
Talking to someone who has had a similar experience can be helpful and our Someone Like Me service can arrange for one of our volunteers to talk to you by email or telephone. Our volunteers have had a personal experience of breast cancer and are trained to provide support.
You can ring the Someone Like Me team on 0345 077 1893, or email them email@example.com so they can then match you to your volunteer.
If you have any questions about our courses please email NRC@breastcancernow.org.
Do call our Helpline if you would like to talk this through or have any further questions. Your call will be confidential, and the number is free from UK landlines and all mobile networks.
The number is 0808 800 6000 (Text relay prefix 18001).
Our opening hours are Monday to Friday 9am - 4pm and 9am -1pm on Saturday. Out of hours you can leave a message and we will call you back when we next open.
Breast Cancer Now Nurse
This thread will now be closed from further replies. If you have any additional questions or would like to provide feedback, please start a new thread.
if it helps I’ve been taking Tamoxifen for 3 months with hardly any side effects. Another of my friends had been taking it for 9 years and also no side effects.
Good luck with your decision
Hi, I was diagnosed with IDC III, HER 2+, ER 3/8, PR 0/8. Initial biopsy showed ER 3/8 from lower outer breast and ER 0/8 from lateral biopsy. Having final chemo this week(have had mast and clearance during Covid crisis), 3 weeks of Rx starting in 4 weeks and targeted therapy for a year. I didn't factor in endocrine therapy until last week when my Oncologist brought it up for the first time as my ER was 3/8. On all correspondence, my ER status is ER negative to weakly positive. Basically, the decision on whether or not to commence endocrine therapy has been left up to me.
I have been doing some research and from what I can determine, endocrine therapy is not very effective in those with a 3/8 ER allred score. From what I can see my options are:
1. Accept that any score above 2 is positive and endocrine therapy should be taken
2. Endocrine therapy is unlikely to be effective with an ER of 3/8 and considering the well documented reports of nasty side effects, it may not be worth it
3. Commence endocrine therapy and if the side effects are unbearable then reconsider whether these outweigh the possible benefits of remaining on such therapy
I'm finding it very difficult to reach a decision, my main concern being that I could start a medication/medications that carry the risk of clots and stroke when the drug itself my not benefit me at all. I've been told my options are Tamoxifen alone, Tamoxifen with Zoladex or aromatase inhibitors with Zoladex.
I would appreciate any feedback please.