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Palbociclib dosage


Re: Palbociclib dosage

Hi 242jane

Thank you for your post.

Like any drug palbociclib can cause side effects. Everyone reacts differently to the drug and some people have more side effects than others. Everyone copes differently and this sometimes means reducing the dose to manage side effects. 

Side effects of palbociclib can have a temporary effect on healthy blood cells in your body which can increase your risk of infection, anaemia and other complications. So, it is important to sometimes to reduce the dosage to ensure your safety and tolerance of the drug, whilst still effectively treating your breast cancer.

Do talk through with your breast care nurse if you have one or your oncologist to understand the reason for your dosage at present. 

You may find it helpful to know that there are other people on palbociclib in a similar situation,  and it sometimes helps to look at what others have posted on the forum about this - these may be found on the secondary breast cancer treatments section of the forum

We provide a number of different services for people living with secondary breast cancer aimed at providing both information and support.

Our helpline team are here for anyone diagnosed with secondary breast cancer. They have time to listen to your concerns, talk things through and signpost you to more support and information.

At times like this, some people find it helpful to talk with others who are going through a similar experience.  We have our living with secondary breast cancer online programme, a secondary breast cancer online discussion forum for sharing information and support.  There is also a weekly Live chat session which runs on Tuesdays at 8.30-9.30pm. 

All services allow people to talk over their experiences and offer support to each other. 

Do call our Helpline if you would like to talk this through or have any further questions. Your call will be confidential, and the number is free from UK landlines and all mobile networks.

The number is 0808 800 6000 (Text relay prefix 18001).

Our opening hours are Monday to Friday 9am - 4pm and 9am -1pm on Saturday. Out of hours you can leave a message and we will call you back when we next open.

Best wishes


Breast Cancer Now Nurse

Please read the Ask Our Nurses disclaimer  Full details on how we collect and use your data can be found in our Privacy Policy


Re: Palbociclib dosage

Hi 242jane

Thanks for posting your question.

We hope to be able to respond to you tomorrow.

In the meantime our Helpline is open from 9am tomorrow if you would like to talk things through. 

If you do phone our Helpline please let us know that you have asked a question on our forum so that we know your query has been answered. Thank you

With best wishes.


Ask Our Nurses Co-ordinator

Please read the Ask Our Nurses disclaimer  Full details on how we collect and use your data can be found in our Privacy Policy


Palbociclib dosage

Hi Can you tell me about the dosage of palbociclib. I’m now on a reduced dose and feel better at 100mg but surely if 125mg is recommended then surely a lower dose is not as effective. Can you explain please?