has anyone lost their appetite with metastic breast cancer not had treatment yet

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Yes I did when I was first diagnosed. I lost a lot of weight, but it improved and now back to my former weight.

I lost about a stone.  I was barely able to eat for about a month. This was before I started targeted treatment and hormonal injections.  I have bone mets and had slightly raised calcium which made me feel sick for several weeks and then it settled and I got my appetite back. I have gained most of the weight back.  I hope it settles for you xx