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Kadcyla Query

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Re: Kadcyla Query

It wasn’t appropriate for my situation - my cancer is not advanced and I wasn’t in the situation where pre-surgery chemo had failed to clear all the cancer. I actually sought a second opinion, to be sure, but the outcome of that verified that Herceptin-only was the better route for me (I cannot have Paclitaxel chemo due to contraindications with another drug I take).


I would have no hesitation having Kadcyla if (heaven forbid) the cancer comes back. It is a clever drug.

 

Rosie

 

 

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Re: Kadcyla Query

Thanks Rosie, that sounds similar to what I’ve read. I’m curious as to how similar it is to the chemotherapy I already revived in terms of blood tests, side effects, need for filgrastim injections etc....all things I can ask consultant when I speak to him

 

do you mind me asking why you didn’t have kadcyla in the end? (Assuming you didn’t from your post)

 

h

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Re: Kadcyla Query

Kadcyla was an option for me so I did some research into it. As I understand it (and medical people - please correct me if I am wrong!), Kadcyla is Herceptin with a small amount of a chemo called Emtansine in it. The Herceptin targets the HER2 protein on the surface of the cancer cell, then ‘injects’ the Emtansine into the cell to kill it off. My understanding was that hair loss is less likely, but you could have some hair thinning. 

Sending best wishes,

Rosie

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Kadcyla Query

Hi all

hoping someone can help with a query. I am currently on a 3 weekly herceptin (trastuzamab) and pertuzamab regime for primary her 2+ breast cancer having had 6 cycles of FEC-T and a single mastectomy with anxcillary node clearance. Following mastectomy there is talk of changing the herceptin/pertuzamab to Kadcyla but I am due to see oncologist in next couple of weeks to talk in more detail.

 

just wondering if anyone else if receiving kadcyla for primary breast cancer and if so whether this drug is actually a chemotherapy (I was hoping I’d seen the back of chemo!) and whether blood tests are needed before each treatment cycle? Any information on side effects also appreciated.....in particular hair loss because there is no chance of be cold capping again!!!!!

 

thanks in advance for any info

hayley x