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Docetaxel after paclitaxel? Onc says no?

10 REPLIES 10
Member

Re: Docetaxel after paclitaxel? Onc says no?

Just about to start docetaxel after 2 years on capecitabine and herceptin due to "massive spread to bones and liver from ct in july to ct in october. Back to hair loss. I was told if this doesnt work nothing so referred to palliative care for pain relief and to be on their books for the future. Having  stronger dose every 3 weeks but can change to weekly if i dont tolerate it well. Research shows 2 years maximum if it works before it becomes ineffective.....hard times ahead

Community Champion

Re: Docetaxel after paclitaxel? Onc says no?

I'm so sorry to hear that your sister littlelizzie has passed away. I responded to her post when she first wrote it and had assumed that treatment options would still be available for her but it seems that her oncologist did realise how difficult things were.  Thinking of you and all her family as you deal with such a loss.

Nicky x

Member

Re: Docetaxel after paclitaxel? Onc says no?

Please accept our condolences on your loss from us all at Breast Cancer Care.

 

Our free Helpline is available for support to everyone, 0808 800 6000. If you would find it helpful, please do call.

 

Best wishes
Anna
Digital Community Officer

Member

Re: Docetaxel after paclitaxel? Onc says no?

So sad to hear about littlelizzie. Thinking of her today, and her big sister who I assumed posted here to let us all know. She earned her wings and is safe now. Will offer a little prayer after posting although she doesn’t need it! She’s flying high.

 

mo

Member

Re: Docetaxel after paclitaxel? Onc says no?

Hello. Just to let you know my sister littlelizzie passed away. I hope you all carry on with you treatments and journey fighting this.

Member

Re: Docetaxel after paclitaxel? Onc says no?

I have just started Vinorelbine, can you tell me about your side effects

Member

Re: Docetaxel after paclitaxel? Onc says no?

Hi Vicky, 

 

Thank you for the reassurance re Eribulin. My oncologist wants to let my body have a rest before going down the chemo road again. I've only had one hormonal since my secondary diagnosis in 2017 so it'll be nice to be off chemo for a while. 

 

Glad to hear Eirbulin is working for you with minimal side effects. Long may it continue!

 

Littlelizzie x

Member

Re: Docetaxel after paclitaxel? Onc says no?

Hi Little Lizzie

 

I was supposed to go on to Taxel but because of damage to my liver went onto Paclitaxol instead. They described it as the gentler sister. It didn't work for me and I am now on Eribulin. I had 4 consecutive treatments that didn't work but after a scan Eribulin has reduced my liver mets and I feel better than I have in 6 months. The only side effects I have are neuropathy in my hands and feet and weak legs. I can tolerate this for good results. 

Sorry that I'm not really answering your question but wanted to give you a heads up on Eribulin.  

 

Good luck with your on going treatment.

 

Vicky

Member

Re: Docetaxel after paclitaxel? Onc says no?

Hi Nicky

Thank you for getting back to me. That does make sense. Wish I could think to ask these types of questions in my appointments! The last chemo vinorelbine knocked me for six and I still feel that it's running around in my body. I've been on chemo for a year so I guess my body does need a break. Hopefully the faslodex and new drug does the trick and I can have a couple of months off from all the nasty side effects.

Hope things are good with you.

 

Littlelizzie xxx

Community Champion

Re: Docetaxel after paclitaxel? Onc says no?

Hi littlelizzie

What a shock to be told this, especially as you have probably been told that there are still plenty of options. I’m guessing that your oncologist has said what she has said as both the taxane chemos are pretty much the same as far as I’ve been told (they are in a different liquid suspension seems to be the main difference but please correct me if I’m wrong). If taxol didn’t work effectively ie eradicate your mets then she must assume putting you through taxotere wont be any more effective but would put a strain on your body. As to Eribulin it is a very effective chemo even when it’s used as a 3rd, 4th or further line of chemo, it also has fewer side effects than some other IV chemos. I think it will depend on how you, and your body, cope with fulvestrant plus the other drug (that I can’t spell!) which I hope will be much easier than your previous chemo and should give your body time to recover from the SEs. After that I would consider getting a second opinion if you are unhappy with your current oncologists viewpoint but still consider having Eribulin or insisting on having it.

Not sure if this helps you much but at least you are going to be having continued treatment, which shouldn’t be anywhere near as harsh on your body and give it time to recover which may also make your oncologist reassess.  

Nicky x

Member

Docetaxel after paclitaxel? Onc says no?

I saw my oncologist yesterday as I had to stop vinorelbine due to side effects. Since Christmas I've lost nearly 2 stone and just want my appetite back! So far with secondaries I've had paclitaxel, gemcitabine, capecitabine and vinorelbine. At initial diagnosis, I had 6 cycles of FEC then tamoxifen for 5 years. I had a couple of months on letrozole which didn't work for me. When I saw my onc yesterday she gave the impression that the only chemo that I could have now would be eirbulin. She has prescribed me faslodex and abemaciclib which I'll start next week but when I mentioned docetaxel she said there was no point as paclitaxel hadn't eradicated the cancer in 2017 (it did dry up the effusion had and I had no progression until the following year). She then said that if the faslodex and abemaciclib didn't work then we may have to have 'the talk' about side effects of treatment versus quality of life. To be honest, I was shocked! I thought I had lots of treatment options available? Has anyone else been told they can't have docetaxel after paclitaxel? Hope everyone is keeping well.

Thanks, 

 

Littlelizzie