Hi Lisa I started examestane on 29th June and everolimus on july 12th ok so far I was same as you on palbo and letrosole for 4 years before it stopped working. I was given lansoprazole for stomach when I started palbo only took it initially and them as needed decided to restart it with E and E treatment and I haven't had any nausea or loss of appetite. Nice to chat to a fellow EEr 👍. Liz x
I have also been given the E&E combo as palpaciclib stopped working after 4years, I am 2 weeks in also the change over has been a bit rough had stomach pains, fatigue, headaches and loss of appetite. Keep me posted on how your going good to know someone else on it.
Hi lesley I was offered everolimus oral combined with the exemestane been tired too prob combo of meds weather and stress. Just on day 12 of exemestane. I am also getting bloods checked for pic3 mutation results take 2 months but apparently this might be an option with a new drug alpelisib which is oral med and used with fulvestrant which is a monthly injection. I was told that if everolimus isn't tolerated I can just have the exemestane . It's all a bit much to take in but these might be an option . Also I know of another person who had iv chemo and is now disease free after15 years with secondaries you say you are 77 thats only a number I'm 67 and hoping to keep fighting this for a long time I'm 4 yearsinto treatment. Sometimes IV isn't pleasant but it can be very effective sounds like your oncologist is totally supportive. Liz xx
Hi Liz. Been on it 3 weeks now just 1 side effect Fatigue, but Oncologist wants me to try Chemo on the drip got 4 weeks to give her my decision scary situation at the moment. Good luck.
Hi lesley I just started exemestane last week was on palbociclib and letrozole for 4 years but some liver involved now so changed to exemestane doing ok so far no side effects.. Am also starting everolimus oral next week if bloods are okay. Liz x
I was on exemestane for eight years after my primary diagnosis. I would have kept going if it can been clinically approved but I had already had extensions beyond normal treatment. I wasn’t really aware of SE; possibly some loose bowels at times and hot flashes at night. I was discharged in 2016 but discovered lots of mets last year. I can’t help but suspect that everything started growing when the exemestane stopped!
