The risk factors that Eyedoc lists for Macular Degeneration, (often referred to as Age Related Macular Degeneration - ARMD) , such as getting old, smoking, UV exposure, genes are quite right and therefore unrelated to Tamoxifen. However, there are other well documented ocular side effects of Tamoxifen including the formation of retinal crystals, which may occur at the macula, (the most sensitive part of the retina), and these changes can have a very similar appearance to some forms of ARMD. Tamoxifen has also been associated with corneal changes, cataract, and very rarely optic neuritis, (affecting the optic nerve). Therefore Moorcow's optometrist, (lovely John), is correct and although these adverse reactions are pretty uncommon, I think it makes sense to have regular, perhaps annual, eye examinations. Incidentally, UK optometrists are qualified - and required -to detect eye disease, and to refer onward to a GP or Ophthalmologist where necessary. If you regularly attend the same practitioner, they will have recorded "baseline data" ie how your eyes looked before you started Tamoxifen, so any subsequent changes can be monitored and reported to the GP/Onc/Ophthalmologist.
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