Hi Irisb, I too had a grade 3 agressive cancer and was given the choice of chemo, the enefit of it being a low percentage, but I grabbed the chance as I was hormone negative, no herceptin et. I understand chemo is very effective on grade 3 tumours. I was also told I had a 50/50 chance of a recurrence, so hair loss or not I went for it.
I got thro it all and am out the other side now, I dont regret my decision for a moment, cos I know i have done all I can .Ok hair loss was an awful thing, but it has grown back now, and I wasn't to poorly on EC chemo.
Good luck with your decision and treatments, only you can make it
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