Breast Cancer Now Forum

Hi Melly, I had to switch after experiencing systemic discomfort with Anastrozole. During the night it was unbearable, possibly as a result of an interaction with medications I already take.  My oncologist said she hadn't every heard of this type of body-wide discomfort before.  I asked her to switch me to Tamoxifen and she agreed.  It has predictable side effects, but is 100% better (for me).  I gained weight, my face is a little puffy, I've lost some hair, and a year in I'm starting to get sore hip joints.  It moves around, resolving in one area and popping up in another. Another day in paradise.  :):) ... View more