Hi Old spice, You need to speak to your oncologist about this. They can do predict tool with you and best advise you. Like any meds letrozole will affect people differently, maybe it will be better for you than Tamoxifen. Another lady I know is fine on Tamoxifen so is staying on that despite being post menopausal now. It's not one size fits all and may take a bit of trial and error, hence the suggestion of coming off for a month. Despite risk of breast cancer many women cannot cope with side effects of normal menopause so take hrt. Most will be fine but statistically c.2 in every 100 will get breast cancer because of it..the other 98 won't. Likewise tamoxifen and letrozole do save lives......but not all, some will still have a recurrence whilst on it, some who come off it won't and vice versa. But no one can tell you which one you will be. Let's face it it's a lottery who gets a recurrence same as who gets it in the first place and we do what feels best for us to cope with that in our own way. Good luck with whatever way you choose x
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