Hi, I had already gone through the menopause when i started taking letrozole in april this year. I was so worried about taking it because i had heard of all these awful potential side effects, and was nearly put off taking it because of all i had read. I decided to try it anyway, as my consultant said most people tolerate it with little or no side effects. I did look at all the brands ingredients first, as some people said they had less side effects with some brands, and decided to go with the Accord brand, as it was the nearest match to the original Femara Brand ingredient wise. I did this, as I knew i would not get prescribed Femara, as its so expensive, but was the original brand that people said they tolerated better. If you want a specific brand, you have to have it written on your prescription to make sure you get dispensed that brand. I have to say, other than occasional nausea in the beginning, I havent really noticed any awful side effects that have affected my daily life. My hair may be a bit drier, and a bit more vaginal dryness, but i get YES VM vaginal moisturiser to help with that. The thing is to try it, and see how you go. Some people may get more side effects than others, so don't be put off taking it. I have wondered whether women that have already gone through the menopause, and already have low estrogen in the body, are less effected by an estrogen blocker?
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I have been looking at the ingredients of Teva and Accord letrozole as the ones my local pharmacies seem to have commonly. I want to choose one which will has less side effects, so decided to look at their ingredients. The ingredients are the same, except Teva has two extra E numbers Accord doesnt have. Tartrazine E102 yellow colouring, the side effects include anxiety, migraine, depression, blurred vision, itching, general weakness, hot sensations, a feeling of suffocation, purple skin patches, and sleep disturbances. It also has E132 which can raise blood pressure slightly. Accord only uses Iron yellow oxide E172, which doesnt seem to have any stated side effects. It also has Hypromellose E464, used as a binder or slow releasing agent, and also used in opthalmic solutions to increase eye lubrication. Teva doesnt have hypromellose. So out of those two, i would prefer to take accord, and not have the added side effects of the 2 extra E numbers, especially the tartrazine E102. Femara has the same ingredients as Accord, other than having a higher macrogol content of 800, to Accords 400. Macrogol is used for constipation. It was interesting comparing the ingredients.
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